(Q42157045)

English

Site-directed mutagenesis of the active site of diacylglycerol kinase alpha: calcium and phosphatidylserine stimulate enzyme activity via distinct mechanisms

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scholarly article

1 reference

Europe PubMed Central

17 October 2017

Site-directed mutagenesis of the active site of diacylglycerol kinase alpha: calcium and phosphatidylserine stimulate enzyme activity via distinct mechanisms (English)

1 reference

Europe PubMed Central

17 October 2017

author name string

Takahiro Abe

1

1 reference

Europe PubMed Central

17 October 2017

Xiaolan Lu

2

1 reference

Europe PubMed Central

17 October 2017

Ying Jiang

3

1 reference

Europe PubMed Central

17 October 2017

Clark E Boccone

4

1 reference

Europe PubMed Central

17 October 2017

Shaomin Qian

5

1 reference

Europe PubMed Central

17 October 2017

Krishna M Vattem

6

1 reference

Europe PubMed Central

17 October 2017

Ronald C Wek

7

1 reference

Europe PubMed Central

17 October 2017

James P Walsh

8

1 reference

Europe PubMed Central

17 October 2017

language of work or name

0 references

publication date

1 November 2003

1 reference

Europe PubMed Central

17 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

17 October 2017

375

1 reference

Europe PubMed Central

17 October 2017

Pt 3

1 reference

Europe PubMed Central

17 October 2017

673-680

1 reference

Europe PubMed Central

17 October 2017

Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are new targets of tumor-promoting phorbol esters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Diacylglyceride kinases, sphingosine kinases and NAD kinases: distant relatives of 6-phosphofructokinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

The structure of a pyrophosphate-dependent phosphofructokinase from the Lyme disease spirochete Borrelia burgdorferi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Diacylglycerol kinases: emerging downstream regulators in cell signaling systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

A new family of phosphotransferases with a P-loop motif.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Diacylglycerol kinase gamma is one of the specific receptors of tumor-promoting phorbol esters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Membrane targeting by C1 and C2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Fatty acids inhibit growth-factor-induced diacylglycerol kinase alpha activation in vascular smooth-muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Phorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Properties and functions of diacylglycerol kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

A domain with homology to neuronal calcium sensors is required for calcium-dependent activation of diacylglycerol kinase alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Facilitation of synaptic transmission by EGL-30 Gqalpha and EGL-8 PLCbeta: DAG binding to UNC-13 is required to stimulate acetylcholine release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Multiple factors influence the binding of a soluble, Ca2+-independent, diacylglycerol kinase to unilamellar phosphoglyceride vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Meta-MEME: motif-based hidden Markov models of protein families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

The C-terminal part of diacylglycerol kinase alpha lacking zinc fingers serves as a catalytic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Arachidonoyl-diacylglycerol kinase from bovine testis. Purification and properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Automated construction and graphical presentation of protein blocks from unaligned sequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Fitting a mixture model by expectation maximization to discover motifs in biopolymers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

The DNA sequences encoding plsB and dgk loci of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Mutations in the active site of Escherichia coli phosphofructokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Occurrence of immunoreactive 80 kDa and non-immunoreactive diacylglycerol kinases in different pig tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Phorbol ester-induced translocation of diacylglycerol kinase from the cytosol to the membrane in Swiss 3T3 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Structural basis of the allosteric behaviour of phosphofructokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Neutral lipid accumulation in the membranes of Escherichia coli mutants lacking diglyceride kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Site-directed mutagenesis in Bacillus stearothermophilus fructose-6-phosphate 1-kinase. Mutation at the substrate-binding site affects allosteric behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Active-site mutants altering the cooperativity of E. coli phosphofructokinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Diacylglycerol kinase from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

29 May 2018

Expression of a catalytically inactive form of diacylglycerol kinase alpha induces sustained signaling through RasGRP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

17 August 2018

Isolation of an individual allosteric interaction in tetrameric phosphofructokinase from Bacillus stearothermophilus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

17 August 2018

Alternative splicing of a novel diacylglycerol kinase in tomato leads to a calmodulin-binding isoform.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

17 August 2018

Hypercooperativity induced by interface mutations in the phosphofructokinase from Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223725

17 August 2018

Role of residue 161 in the allosteric transitions of two bacterial phosphofructokinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12908872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutagenesis identifies catalytic residues in the active site of Escherichia coli phosphofructokinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12908872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subtype-specific translocation of diacylglycerol kinase alpha and gamma and its correlation with protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/12908872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12908872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of rat kidney sphingosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12908872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and transcriptional analysis of new members of the sigmaB regulon in Bacillus subtilis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12908872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of phosphatidic acid to the protein-tyrosine phosphatase SHP-1 as a basis for activity modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12908872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20031052

1 reference

Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

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