(Q42163509)

English

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration

scientific article published on 12 May 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

intervertebral disc cell

1 reference

based on heuristic

inferred from title

Anthony J. Freemont

3

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

author name string

S Jane Millward-Sadler

1

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Patrick W Costello

2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Judith A Hoyland

4

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

publication date

12 May 2009

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Arthritis Research and Therapy

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

11

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

3

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

R65

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

https://scigraph.springernature.com/pub.10.1186/ar2693

0 references

Phosphorylation of extracellular signal-regulated kinase 1/2, p38 mitogen-activated protein kinase and nuclear translocation of nuclear factor-kappaB are involved in upregulation of matrix metalloproteinase-9 by tumour necrosis factor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Matrix synthesis and degradation in human intervertebral disc degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Tumor necrosis factor-alpha modulates matrix production and catabolism in nucleus pulposus tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

26 October 2017

Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

29 May 2018

Diverging mechanisms for TNF-alpha receptors in normal mouse brains and in functional recovery after injury: From gene to behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

17 August 2018

Human disc degeneration is associated with increased MMP 7 expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

17 August 2018

A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

17 August 2018

Preferential induction of prodestructive matrix metalloproteinase-1 and proinflammatory interleukin 6 and prostaglandin E2 in rheumatoid arthritis synovial fibroblasts via tumor necrosis factor receptor-55.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

17 August 2018

Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

17 August 2018

The economic burden of back pain in the UK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714110

17 August 2018

Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of interleukin-1beta and tumor necrosis factor-alpha on expression of matrix-related genes by cultured equine articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen-induced arthritis in TNF receptor-1-deficient mice: TNF receptor-2 can modulate arthritis in the absence of TNF receptor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of gelatin-degrading matrix metalloproteinases ('type IV collagenases') and inhibitors by articular chondrocytes during their dedifferentiation by serial subcultures and under stimulation by interleukin-1 and tumor necrosis factor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of the in vivo production of interleukin-1 receptor antagonist in patients with rheumatoid arthritis. Pathogenetic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha, anti-IL-1 alpha/beta, and IL-1Ra

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunolocalization of major interstitial collagen types in human lumbar intervertebral discs of various ages

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and Distribution of Tumor Necrosis Factor Alpha in Human Lumbar Intervertebral Discs: A Study in Surgical Specimen and Autopsy Controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Tissue Distribution of TNF- , TNF- -Receptors, and the Activating TNF- -Converting Enzyme Suggests Activation of the TNF- System in the Aging Intervertebral Disc

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

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