(Q42185363)

18 October 2017

Discovery of 1,5-disubstituted pyridones: a new class of positive allosteric modulators of the metabotropic glutamate 2 receptor (English)

1 reference

18 October 2017

23

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18 October 2017

24

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18 October 2017

25

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18 October 2017

27

Emmanuel Le Poul

1 reference

18 October 2017

Jose María Cid

1

1 reference

18 October 2017

Guillaume Duvey

2

1 reference

18 October 2017

Philippe Cluzeau

3

1 reference

18 October 2017

Vanthea Nhem

4

1 reference

18 October 2017

Karim Macary

5

1 reference

18 October 2017

Alexandre Raux

6

1 reference

18 October 2017

Nicolas Poirier

7

1 reference

18 October 2017

Jessica Muller

8

1 reference

18 October 2017

Christelle Boléa

9

1 reference

18 October 2017

Terry Finn

10

1 reference

18 October 2017

Sonia Poli

11

1 reference

18 October 2017

Mark Epping-Jordan

12

1 reference

18 October 2017

Emilie Chamelot

13

1 reference

18 October 2017

Francis Derouet

14

1 reference

18 October 2017

Francoise Girard

15

1 reference

18 October 2017

Gregor J Macdonald

16

1 reference

18 October 2017

Juan Antonio Vega

17

1 reference

18 October 2017

Ana Isabel de Lucas

18

1 reference

18 October 2017

Encarnación Matesanz

19

1 reference

18 October 2017

Hilde Lavreysen

20

1 reference

18 October 2017

María Lourdes Linares

21

1 reference

18 October 2017

Daniel Oehlrich

22

1 reference

18 October 2017

Jose Ignacio Andrés

26

1 reference

18 October 2017

Hassan Imogai

28

1 reference

18 October 2017

Robert Lutjens

29

1 reference

18 October 2017

Jean-Philippe Rocher

30

1 reference

18 October 2017

23 August 2010

1 reference

ACS Chemical Neuroscience

18 October 2017

1 reference

18 October 2017

1

1 reference

18 October 2017

12

1 reference

18 October 2017

788-795

1 reference

Progress in the developement of positive allosteric modulators of the metabotropic glutamate receptor 2.

18 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Metabotropic glutamate receptors as novel targets for anxiety and stress disorders

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 2: 4-thiopyridyl acetophenones as non-tetrazole containing mGlu2 receptor potentiators.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

LY354740, an mGlu2/3 receptor agonist as a novel approach to treat anxiety/stress

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl)pyrid-3-ylmethylamine

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Preclinical pharmacology of mGlu2/3 receptor agonists: novel agents for schizophrenia?

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039).

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368638

Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22778815

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22778815

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CN1000638

1 reference

18 October 2017

1 reference

18 October 2017

PubMed publication ID

22778815

1 reference