(Q42224632)

19 October 2017

Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe (English)

1 reference

19 October 2017

9

Craig W Lindsley

1 reference

19 October 2017

Eric Delpire

1

1 reference

19 October 2017

Aleksandra Baranczak

2

1 reference

19 October 2017

Alex G Waterson

3

1 reference

19 October 2017

Kwangho Kim

4

1 reference

19 October 2017

Nathan Kett

5

1 reference

19 October 2017

Ryan D Morrison

6

1 reference

19 October 2017

J Scott Daniels

7

1 reference

19 October 2017

C David Weaver

8

1 reference

19 October 2017

language of work or name

English

0 references

publication date

7 June 2012

1 reference

Bioorganic & Medicinal Chemistry Letters

19 October 2017

1 reference

19 October 2017

22

1 reference

19 October 2017

14

1 reference

19 October 2017

4532-4535

1 reference

Inhibition of KCC2 in mouse spinal cord neurons leads to hypersensitivity to thermal stimulation

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Application of combinatorial chemistry science on modern drug discovery

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Loose ligation of the sciatic nerve is associated with TrkB receptor-dependent decreases in KCC2 protein levels in the ipsilateral spinal dorsal horn

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Diabetes affects the expression of GABA and potassium chloride cotransporter in the spinal cord: a study in streptozotocin diabetic rats

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Reduced potassium-chloride co-transporter expression in spinal cord dorsal horn neurons contributes to inflammatory pain hypersensitivity in rats

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389279

Expression changes of cation chloride cotransporters in the rat spinal cord following intraplantar formalin

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22727639

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2012.05.126

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

22727639

1 reference