(Q42247303)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Deborah Young

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

author name string

Patricia A Lawlor

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Ross J Bland

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Pritam Das

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Robert W Price

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Vallie Holloway

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Lisa Smithson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Matthew J During

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Todd E Golde

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

publication date

9 June 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

Molecular Neurodegeneration

31 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/1750-1326-2-11

31 December 2019

exact match

0 references

cites work

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26 October 2017

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Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

26 October 2017

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A specific amyloid-beta protein assembly in the brain impairs memory

26 October 2017

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Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model

26 October 2017

1 reference

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Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo.

26 October 2017

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Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

26 October 2017

1 reference

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Regulation of NMDA receptor trafficking by amyloid-beta

26 October 2017

1 reference

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What is the dominant Abeta species in human brain tissue? A review

26 October 2017

1 reference

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Using animal models to determine the significance of complement activation in Alzheimer's disease

26 October 2017

1 reference

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Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.

26 October 2017

1 reference

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Regional dissociations within the hippocampus--memory and anxiety.

26 October 2017

1 reference

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Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

26 October 2017

1 reference

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Recombinant AAV-mediated gene delivery to the central nervous system.

26 October 2017

1 reference

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Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

26 October 2017

1 reference

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

26 October 2017

1 reference

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Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease

26 October 2017

1 reference

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Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

26 October 2017

1 reference

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Reversible memory loss in a mouse transgenic model of Alzheimer's disease

26 October 2017

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

26 October 2017

1 reference

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alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

26 October 2017

1 reference

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Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length.

26 October 2017

1 reference

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The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

26 October 2017

1 reference

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Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

26 October 2017

1 reference

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Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides

26 October 2017

1 reference

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Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

26 October 2017

1 reference

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A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

26 October 2017

1 reference

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

26 October 2017

1 reference

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Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides

26 October 2017

1 reference

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The beta-amyloid precursor protein and its derivatives: from biology to learning and memory processes

26 October 2017

1 reference

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Intraneuronal aggregate formation and cell death after viral expression of expanded polyglutamine tracts in the adult rat brain.

26 October 2017

1 reference

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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

26 October 2017

1 reference

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A stop-codon mutation in the BRI gene associated with familial British dementia

26 October 2017

1 reference

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

26 October 2017

1 reference

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

26 October 2017

1 reference

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Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain

26 October 2017

1 reference

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Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor.

26 October 2017

1 reference

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

26 October 2017

1 reference

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Lesions of the ventral hippocampus, but not the dorsal hippocampus, impair conditioned fear expression and inhibitory avoidance on the elevated T-maze.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Effects of lesions to the dorsal and ventral hippocampus on defensive behaviors in rats.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Progressive cognitive decline in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Effects of a novel cognitive enhancer, spiro[imidazo-[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446), on learning impairments induced by amyloid-beta1-40 in the rat.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid Beta and impairment of learning and memory

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Neurochemical and behavioral effects of the intrahippocampal co-injection of beta-amyloid protein1-40 and ibotenic acid in rats

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Soluble Arctic amyloid beta protein inhibits hippocampal long-term potentiation in vivo

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

A secreted form of the beta-amyloid precursor protein (sAPP695) improves spatial recognition memory in OF1 mice

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Ventral hippocampal lesions affect anxiety but not spatial learning

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Nicotine enhances the depressive actions of A beta 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Development and optimization of adeno-associated virus vector transfer into the central nervous system

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40).

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906777

17 August 2018

Identifiers

DOI

10.1186/1750-1326-2-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 December 2019

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1750-1326-2-11

Fatcat ID

release_e2kut7rox5fcpc7d5kmqyphqq4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/e2kut7rox5fcpc7d5kmqyphqq4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17559680%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference