(Q42252961)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice (English)

1 reference

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10 March 2020

5

1 reference

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10 March 2020

author name string

Da-Hai Yu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Robert A Waterland

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Pumin Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Deborah Schady

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Yongtao Guan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Manasi Gadkari

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Lanlan Shen

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

language of work or name

English

0 references

publication date

25 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

10 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

124

1 reference

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10 March 2020

issue

9

1 reference

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10 March 2020

page(s)

3708-3712

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island

10 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

A decade of exploring the cancer epigenome - biological and translational implications

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Widespread and tissue specific age-related DNA methylation changes in mice.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

The Ink4/Arf locus is a barrier for iPS cell reprogramming

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Derivation of hematopoietic stem cells from murine embryonic stem cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

The history of cancer epigenetics

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

The power and the promise of DNA methylation markers

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Altered methylation patterns in cancer cell genomes: cause or consequence?

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

p16(MTS-1/CDKN2/INK4a) in cancer progression

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

The INK4A/ARF locus and its two gene products

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

The inheritance of epigenetic defects

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

DNA methylation and environmental exposures in human hepatocellular carcinoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Identification of genetic elements that autonomously determine DNA methylation states.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Accelerated age-related CpG island methylation in ulcerative colitis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151219

Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylation

1 December 2018

1 reference

12 December 2020

Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis--A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from

1 reference

12 December 2020

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1 reference

12 December 2020

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI76507

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

25061879

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061879%20AND%20SRC:MED&resulttype=core&format=json