(Q42252979)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

7

1 reference

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1 March 2020

Isabel Lastres-Becker

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Tomasz Jaworski

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Sebastian Kügler

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Nadia G Innamorato

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Alberto Rábano

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Fred Van Leuven

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

25 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

137

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

Pt 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

78-91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277722%20AND%20SRC:MED&resulttype=core&format=json

Loss of transcription factor nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) leads to dysregulation of immune functions, redox homeostasis, and intracellular signaling in dendritic cells

1 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Regulation of tau pathology by the microglial fractalkine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Review: activation patterns of microglia and their identification in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Basic principles and emerging concepts in the redox control of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

The liberation of fractalkine in the dorsal horn requires microglial cathepsin S.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Sulforaphane improves cognitive function administered following traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Transgenic mouse model of tau pathology in astrocytes leading to nervous system degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Inflammation and oxidative damage in Alzheimer's disease: friend or foe?

21 January 2018

1 reference

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Mechanisms of cell protection by heme oxygenase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Fractalkine and fractalkine receptors in human neurons and glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

siRNA knockdown of ADAM-10, but not ADAM-17, significantly reduces fractalkine shedding following pro-inflammatory cytokine treatment in a human adult brain endothelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Regulation of CX3CL1/fractalkine expression in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Role of microglial redox balance in modulation of neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

The transcription factor Nrf2 is a therapeutic target against brain inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Dendritic degeneration, neurovascular defects, and inflammation precede neuronal loss in a mouse model for tau-mediated neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Changes in the levels of plasma soluble fractalkine in patients with mild cognitive impairment and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Amyloid-beta, tau protein, and oxidative changes as a physiological compensatory mechanism to maintain CNS plasticity under Alzheimer's disease and other neurodegenerative conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Review: experimental manipulations of microglia in mouse models of Alzheimer's pathology: activation reduces amyloid but hastens tau pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Chemokines and chemokine receptors: multipurpose players in neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

How to get from here to there: macrophage recruitment in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Identification of age-specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity in the aging rat liver?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

When NRF2 talks, who's listening?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Synergistic stimulation, by tumor necrosis factor-alpha and interferon-gamma, of fractalkine expression in human astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323

Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT323