(Q42277191)

19 October 2017

Quality control of mitochondria during aging: is there a good and a bad side of mitochondrial dynamics? (English)

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19 October 2017

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1

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19 October 2017

Heinz D Osiewacz

2

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PubMed ID

23359437

19 October 2017

Andreas S Reichert

series ordinal

3

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PubMed ID

23359437

19 October 2017

language of work or name

English

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publication date

29 January 2013

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19 October 2017

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19 October 2017

35

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19 October 2017

4

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19 October 2017

314-322

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Mitochondrial diseases in man and mouse

19 October 2017

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial free radical generation and lifespan control in the fungal aging model Podospora anserina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

A systems biological analysis links ROS metabolism to mitochondrial protein quality control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Increasing mitochondrial superoxide dismutase abundance leads to impairments in protein quality control and ROS scavenging systems and to lifespan shortening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Biological roles of the Podospora anserina mitochondrial Lon protease and the importance of its N-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Increasing organismal healthspan by enhancing mitochondrial protein quality control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

A stress-responsive system for mitochondrial protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial quality control by the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

A vesicular transport pathway shuttles cargo from mitochondria to lysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

21 January 2018

Mechanisms of mitophagy

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Staying cool in difficult times: mitochondrial dynamics, quality control and the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Quality control of mitochondria: protection against neurodegeneration and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial quality control: an integrated network of pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial protein quality control: implications in ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Impaired quality control of mitochondria: aging from a new perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Deceleration of fusion-fission cycles improves mitochondrial quality control during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Functions and dysfunctions of mitochondrial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Emerging roles of mitochondrial membrane dynamics in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial fusion and fission in cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

The SUMO protease SENP5 is required to maintain mitochondrial morphology and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Ubiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Selective elimination of mitochondria from living cells induced by inhibitors of bioenergetic functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Selective degradation of mitochondria by mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

A novel cell-free mitochondrial fusion assay amenable for high-throughput screenings of fusion modulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

The intracellular redox state is a core determinant of mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

RALA and RALBP1 regulate mitochondrial fission at mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

SLP-2 is required for stress-induced mitochondrial hyperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Genes, mitochondria and aging in filamentous fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial-nuclear interactions and lifespan control in fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Insertion of a foreign nucleotide sequence into mitochondrial DNA causes senescence in Neurospora intermedia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

On the timing and the extent of clonal expansion of mtDNA deletions: evidence from single-molecule PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

An extrachromosomal plasmid is the etiological precursor of kalDNA insertion sequences in the mitochrondrial chromosome of senescent neurospora

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200125

21 January 2018

Identifiers

DOI

10.1002/BIES.201200125

1 reference

19 October 2017

1 reference

PubMed ID

23359437