(Q47233712)

12 January 2018

title

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy (English)

1 reference

12 January 2018

1 reference

Belém Sampaio-marques

1

1 reference

12 January 2018

Sandra Tenreiro

5

1 reference

12 January 2018

Paula Ludovico

10

1 reference

12 January 2018

Carolina Felgueiras

Carolina Felgueiras

2

0 references

Alexandra Silva

Alexandra Silva

3

0 references

Andreas S Reichert

Andreas S Reichert

7

0 references

Vanessa Franssens

6

Vanessa Franssens

1 reference

12 January 2018

Joris Winderickx

9

Joris Winderickx

1 reference

12 January 2018

author name string

Márcio Rodrigues

4

1 reference

12 January 2018

Tiago F Outeiro

8

1 reference

12 January 2018

publication date

23 August 2012

1 reference

12 January 2018

published in

Autophagy

1 reference

12 January 2018

volume

8

1 reference

12 January 2018

issue

10

1 reference

12 January 2018

page(s)

1494-1509

1 reference

12 January 2018

Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

cites work

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Genetics of Parkinson disease: paradigm shifts and future prospects.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

α-Synuclein: membrane interactions and toxicity in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Diversity in the regulation of autophagy and mitophagy: lessons from Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Cellular strategies for controlling protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Role of the ubiquitin proteasome system in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Alpha-synuclein alters proteasome function, protein synthesis, and stationary phase viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Altered proteasomal function in sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

The role of autophagy in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Mutant A53T alpha-synuclein induces neuronal death by increasing mitochondrial autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Mitophagy: the latest problem for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Mitochondrial α-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Yeast unfolds the road map toward alpha-synuclein-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Yeast chronological lifespan and proteotoxic stress: is autophagy good or bad?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Autophagy in health and disease: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Methods for monitoring autophagy from yeast to human

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Regulation of APG14 expression by the GATA-type transcription factor Gln3p

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Endoplasmic reticulum stress triggers autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

The molecular mechanism of mitochondria autophagy in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Chapter 3 The Quantitative Pho8Δ60 Assay of Nonspecific Autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

The molecular machinery of autophagy: unanswered questions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Atg32 is a mitochondrial protein that confers selectivity during mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Phosphorylation, lipid raft interaction and traffic of alpha-synuclein in a yeast model for Parkinson

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

The chronological life span of Saccharomyces cerevisiae to study mitochondrial dysfunction and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Regulation of autophagy by ROS: physiology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Regulation mechanisms and signaling pathways of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Recent developments in yeast aging

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Beer and bread to brains and beyond: can yeast cells teach us about neurodegenerative disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Huntingtin localization in brains of normal and Huntington's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Huntington's disease: degradation of mutant huntingtin by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

alpha-Synuclein budding yeast model: toxicity enhanced by impaired proteasome and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

alpha-synuclein promotes mitochondrial deficit and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Longevity-relevant regulation of autophagy at the level of the acetylproteome.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

Atg32 Is a tag for mitochondria degradation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.21275

21 January 2018

Identifiers

DOI

10.4161/AUTO.21275

1 reference

12 January 2018

PubMed ID

22914317

1 reference

12 January 2018