(Q42314996)

English

The interdependence of antibody C and V regions on specificity and affinity: significant implications for the engineering of therapeutic antibodies

scientific article published on August 2013

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scholarly article

1 reference

Europe PubMed Central

25 October 2017

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The interdependence of antibody C and V regions on specificity and affinity: significant implications for the engineering of therapeutic antibodies (English)

1 reference

Europe PubMed Central

25 October 2017

Joshua D Nosanchuk

1

object named as

Joshua D Nosanchuk

1 reference

Europe PubMed Central

25 October 2017

publication date

1 August 2013

1 reference

Europe PubMed Central

25 October 2017

1 reference

Europe PubMed Central

25 October 2017

4

1 reference

Europe PubMed Central

25 October 2017

6

1 reference

Europe PubMed Central

25 October 2017

439-440

1 reference

Europe PubMed Central

25 October 2017

Global structures of IgG isotypes expressing identical variable regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Constant domains influence binding of mouse-human chimeric antibodies to the capsular polypeptide of Bacillus anthracis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

The constant region affects antigen binding of antibodies to DNA by altering secondary structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

IgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Structure of a human IgA1 Fab fragment at 1.55 Å resolution: potential effect of the constant domains on antigen-affinity modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Variable region identical immunoglobulins differing in isotype express different paratopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Protection by anti-beta-glucan antibodies is associated with restricted beta-1,3 glucan binding specificity and inhibition of fungal growth and adherence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Exchanging murine and human immunoglobulin constant chains affects the kinetics and thermodynamics of antigen binding and chimeric antibody autoreactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Human immunoglobulin G2 (IgG2) and IgG4, but not IgG1 or IgG3, protect mice against Cryptococcus neoformans infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Human constant regions influence the antibody binding characteristics of mouse-human chimeric IgG subclasses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Carbon-13 NMR study of switch variant anti-dansyl antibodies: antigen binding and domain-domain interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

25 October 2017

Isothermal titration calorimetry reveals differential binding thermodynamics of variable region-identical antibodies differing in constant region for a univalent ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

17 August 2018

Variable-region-identical antibodies differing in isotype demonstrate differences in fine specificity and idiotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

17 August 2018

The hydrolysis of rabbit y-globulin and antibodies with crystalline papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5359721

17 August 2018

The Immunoglobulin Heavy Chain Constant Region Affects Kinetic and Thermodynamic Parameters of Antibody Variable Region Interactions with Antigen

1 reference

https://api.crossref.org/works/10.4161%2FVIRU.26153

21 January 2018

Role of heavy chain constant domains in antibody-antigen interaction. Apparent specificity differences among streptococcal IgG antibodies expressing identical variable domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding properties and anti-bacterial activities of V-region identical, human IgG and IgM antibodies, against group B Neisseria meningitidis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isotype can affect the fine specificity of an antibody for a polysaccharide antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Can isotype switch modulate antigen-binding affinity and influence clonal selection?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/VIRU.26153

1 reference

Europe PubMed Central

25 October 2017

1 reference

Europe PubMed Central

25 October 2017

1 reference

Europe PubMed Central

25 October 2017

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