(Q42349186)

English

The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology

scientific article published on 23 May 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

0 references

The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology (English)

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

sickle-cell disease

0 references

pathophysiology

1 reference

based on heuristic

inferred from title

reactive oxygen species

1 reference

based on heuristic

inferred from title

Mark T. Gladwin

3

object named as

Mark T Gladwin

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

author name string

Megan L Krajewski

1

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

Lewis L Hsu

2

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

publication date

23 May 2008

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

American Journal of Physiology Heart and Circulatory Physiology

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

295

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

H4-7

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Sickle cell disease vasculopathy: a state of nitric oxide resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Heme, heme oxygenase, and ferritin: how the vascular endothelium survives (and dies) in an iron-rich environment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Protective effect of arginine on oxidative stress in transgenic sickle mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Severity of pulmonary hypertension during vaso-occlusive pain crisis and exercise in patients with sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Deconstructing endothelial dysfunction: soluble guanylyl cyclase oxidation and the NO resistance syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Hemolysis-associated priapism in sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Hemolytic anemia-associated pulmonary hypertension in sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Divergent nitric oxide bioavailability in men and women with sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Endothelial function. From vascular biology to clinical applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Direct real-time evaluation of nitration with green fluorescent protein in solution and within human cells reveals the impact of nitrogen dioxide vs. peroxynitrite mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

29 May 2018

Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

17 August 2018

Endothelial cell NADPH oxidase mediates the cerebral microvascular dysfunction in sickle cell transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

17 August 2018

Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

17 August 2018

Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

17 August 2018

A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

17 August 2018

Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494755

17 August 2018

Modulation of Gardos channel activity by cytokines in sickle erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of tyrosine nitration by peroxynitrite generated at physiological pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.00499.2008

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 October 2017

ResearchGate publication ID

0 references

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