(Q42411842)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16511067%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Structural analysis of caspase-1 inhibitors derived from Tethering (English)

1 reference

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17 January 2020

1

1 reference

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17 January 2020

2

Bruce T Fahr

1 reference

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17 January 2020

9

Michael J Romanowski

1 reference

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17 January 2020

4

Joni W Lam

1 reference

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17 January 2020

7

Hans E Purkey

1 reference

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17 January 2020

author name string

Michelle M Sopko

3

1 reference

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17 January 2020

Nathan D Waal

5

1 reference

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17 January 2020

Brian C Raimundo

6

1 reference

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17 January 2020

Phuongly Pham

8

1 reference

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17 January 2020

publication date

9 April 2005

1 reference

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Acta Crystallographica Section F: Structural Biology Communications

17 January 2020

published in

1 reference

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17 January 2020

volume

61

1 reference

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17 January 2020

issue

Pt 5

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17 January 2020

page(s)

451-458

1 reference

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Molecular mechanisms of caspase regulation during apoptosis

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Refinement of macromolecular structures by the maximum-likelihood method

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Making drugs on proteins: site-directed ligand discovery for fragment-based lead assembly

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Tethering: fragment-based drug discovery

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Prospects for caspase inhibitors.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Discovery and characterization of cooperative ligand binding in the adaptive region of interleukin-2

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

In situ assembly of enzyme inhibitors using extended tethering

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Implementation of molecular replacement in AMoRe

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

The finer things in X-ray diffraction data collection

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Incorporation of prior phase information strengthens maximum-likelihood structure refinement

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Efficient anisotropic refinement of macromolecular structures using FFT

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Autoproteolytic activation of pro-caspases by oligomerization

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Proteases, proteolysis, and apoptosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE)

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Structure and mechanism of interleukin-1 beta converting enzyme

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Improved methods for building protein models in electron density maps and the location of errors in these models

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Molecular cloning of the interleukin-1 beta converting enzyme

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Expression, refolding, and autocatalytic proteolytic processing of the interleukin-1 beta-converting enzyme precursor

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952309

Identification of potent and novel small-molecule inhibitors of caspase-3

16 August 2018

1 reference

12 December 2020

High-throughput screening of enzyme inhibitors: simultaneous determination of tight-binding inhibition constants and enzyme concentration

1 reference

12 December 2020

IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha

1 reference

12 December 2020

Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme

1 reference

12 December 2020

Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin-1 beta converting enzyme (ICE)

1 reference

12 December 2020

10.1107/S1744309105010109

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16511067%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16511067%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

16511067

1 reference