(Q42432966)

English

Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in trypanosomes

scientific article published on 21 May 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in trypanosomes (English)

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Mohamed A. Ismail

3

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

object named as

Tanja Wenzler

9

0 references

author name string

Amanda M Mathis

1

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Arlene S Bridges

2

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Arvind Kumar

4

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Iris Francesconi

5

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Mariappan Anbazhagan

6

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Qiyue Hu

7

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Farial A Tanious

8

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Janelle Saulter

10

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

W David Wilson

11

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Reto Brun

12

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

David W Boykin

13

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Richard R Tidwell

14

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

James Edwin Hall

15

1 reference

Europe PubMed Central

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31 October 2017

language of work or name

0 references

publication date

21 May 2007

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

51

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

2801-2810

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Accumulation and intracellular distribution of antitrypanosomal diamidine compounds DB75 and DB820 in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Diamidines as antitrypanosomal, antileishmanial and antimalarial agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Chemotherapy of trypanosomiases and leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Dications that target the DNA minor groove: compound design and preparation, DNA interactions, cellular distribution and biological activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Distribution of furamidine analogues in tumor cells: influence of the number of positive charges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Transporters in African trypanosomes: role in drug action and resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Acidocalcisome: A novel Ca2+ storage compartment in trypanosomatids and apicomplexan parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Evaluation of drug-nucleic acid interactions by thermal melting curves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Pharmacology of diminazene: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Dicationic diarylfurans as anti-Pneumocystis carinii agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Localization of polyphosphates in Saccharomyces fragilis, as revealed by 4',6-diamidino-2-phenylindole fluorescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Effects of trypanocides on the fine structure of target organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)furans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

28 May 2018

Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Molecular pharmacology of adenosine transport in Trypanosoma brucei: P1/P2 revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Thiophene-based diamidine forms a "super" at binding minor groove agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Synthesis and antiprotozoal activity of aza-analogues of furamidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria depending on the amidine substitution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Drug-promoted cleavage of kinetoplast DNA minicircles. Evidence for type II topoisomerase activity in trypanosome mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932548

16 August 2018

Antiparasitic activity of aromatic diamidines is related to apoptosis-like death in Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/17517831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, DNA Affinity, and Antiprotozoal Activity of Linear Dications: Terphenyl Diamidines and Analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17517831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00005-07

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

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