(Q42434849)

31 October 2017

title

Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system (English)

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31 October 2017

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Richard Killick

8

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Christopher Thrasivoulou

object named as

Christopher Thrasivoulou

6

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Simon Lovestone

object named as

Simon Lovestone

7

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author name string

Raya Al-Shawi

1

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31 October 2017

Angela Hafner

2

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31 October 2017

Jessica Olsen

3

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31 October 2017

Soyon Chun

4

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31 October 2017

Saba Raza

5

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31 October 2017

Paul Simons

9

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31 October 2017

Timothy Cowen

10

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31 October 2017

language of work or name

English

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publication date

1 April 2008

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European Journal of Neuroscience

31 October 2017

published in

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31 October 2017

volume

27

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31 October 2017

issue

8

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31 October 2017

page(s)

2103-2114

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Mature pig oligodendrocytes rapidly process human recombinant pro-nerve growth factor and do not undergo cell death.

31 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Grasping objects: the cortical mechanisms of visuomotor transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Selective vulnerability in adult and ageing mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Plasticity in adult and ageing sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Restricted diet rescues rat enteric motor neurones from age related cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Hippocampal NGF levels are not reduced in the aged Fischer 344 rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Monoclonal antibody rat 401 recognizes Schwann cells in mature and developing peripheral nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

The role of NGF uptake in selective vulnerability to cell death in ageing sympathetic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Responsiveness of sympathetic and sensory iridial nerves to NGF treatment in young and aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Loss of calbindin-D28k from aging human cholinergic basal forebrain: relation to neuronal loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Impaired spatial learning in aged rats is associated with loss of p75-positive neurons in the basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Regulation of cell survival by secreted proneurotrophins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Sortilin is essential for proNGF-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Serum-free culture of dissociated, purified adult and aged sympathetic neurons and quantitative assays of growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Differential regulation of survival and growth in adult sympathetic neurons: an in vitro study of neurotrophin responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Induction of apoptosis by the low-affinity NGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Memory impairment in aged primates is associated with focal death of cortical neurons and atrophy of subcortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

Regulation of C. elegans life-span by insulinlike signaling in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06152.X

10.1111/J.1460-9568.2008.06152.X

21 January 2018

Identifiers

DOI

1 reference

31 October 2017

1 reference