(Q42435326)

English

Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons

scientific article published on 19 March 2008

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scholarly article

1 reference

Europe PubMed Central

31 October 2017

Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons (English)

1 reference

Europe PubMed Central

31 October 2017

Mark H. Tuszynski

6

object named as

Mark Tuszynski

1 reference

Europe PubMed Central

31 October 2017

author name string

Kathie M Bishop

1

1 reference

Europe PubMed Central

31 October 2017

Eva K Hofer

2

1 reference

Europe PubMed Central

31 October 2017

Arpesh Mehta

3

1 reference

Europe PubMed Central

31 October 2017

Anthony Ramirez

4

1 reference

Europe PubMed Central

31 October 2017

Liangwu Sun

5

1 reference

Europe PubMed Central

31 October 2017

Raymond T Bartus

7

1 reference

Europe PubMed Central

31 October 2017

language of work or name

0 references

publication date

19 March 2008

1 reference

Europe PubMed Central

31 October 2017

Experimental Neurology

1 reference

Europe PubMed Central

31 October 2017

211

1 reference

Europe PubMed Central

31 October 2017

2

1 reference

Europe PubMed Central

31 October 2017

574-584

1 reference

Europe PubMed Central

31 October 2017

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1 reference

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1 reference

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28 May 2018

Cholinesterase inhibitors for Alzheimer's disease

1 reference

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Progression of age-associated cognitive impairment correlates with quantitative and qualitative loss of TrkA receptor protein in nucleus basalis and cortex

1 reference

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28 May 2018

Modulation of sensory inputs and ectopic presence of Schwann cells depend upon the route and duration of nerve growth factor administration

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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28 May 2018

Amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of NGF.

1 reference

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1 reference

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28 May 2018

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

1 reference

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28 May 2018

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

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28 May 2018

Use of cholinesterase inhibitors for treatment of Alzheimer disease

1 reference

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28 May 2018

The functional observational battery in adult and developing rats

1 reference

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28 May 2018

Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation

1 reference

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28 May 2018

Impaired spatial learning in aged rats is associated with loss of p75-positive neurons in the basal forebrain

1 reference

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28 May 2018

The cholinergic neuronal phenotype in Alzheimer's disease

1 reference

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28 May 2018

On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis

1 reference

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28 May 2018

Immunohistochemical and neurochemical correlates of learning deficits in aged rats

1 reference

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28 May 2018

Neuroplasticity failure in Alzheimer's disease: bridging the gap between plaques and tangles

1 reference

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28 May 2018

Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy

1 reference

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28 May 2018

Cognitive functions of the basal forebrain

1 reference

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28 May 2018

Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases

1 reference

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28 May 2018

Removal of cholinergic input to rat posterior parietal cortex disrupts incremental processing of conditioned stimuli.

1 reference

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28 May 2018

Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element.

1 reference

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28 May 2018

Cortical map reorganization enabled by nucleus basalis activity

1 reference

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28 May 2018

Effects of scopolamine on delayed-matching-to-sample and paired associates tests of visual memory and learning in human subjects: comparison with diazepam and implications for dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Development of neurotrophic factor therapy for Alzheimer's disease.

1 reference

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28 May 2018

Long-term functional recovery from age-induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain

1 reference

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28 May 2018

Effects of intraventricular encapsulated hNGF-secreting fibroblasts in aged rats.

1 reference

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28 May 2018

3-D reconstruction of the cholinergic basal forebrain system in young and aged rats.

1 reference

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28 May 2018

Distribution of [125I]nerve growth factor in the rat brain following a single intraventricular injection: correlation with the topographical distribution of trkA messenger RNA-expressing cells

1 reference

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28 May 2018

Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits.

1 reference

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28 May 2018

Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery

1 reference

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28 May 2018

Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration

1 reference

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28 May 2018

Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis

1 reference

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28 May 2018

Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

1 reference

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28 May 2018

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

1 reference

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28 May 2018

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

1 reference

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28 May 2018

Nerve growth factor treatment after brain injury prevents neuronal death

1 reference

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28 May 2018

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

1 reference

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28 May 2018

Role of neurotrophic factors in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Potential use of nerve growth factor to treat Alzheimer's disease

1 reference

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28 May 2018

Mouse nerve growth factor prevents degeneration of axotomized basal forebrain cholinergic neurons in the monkey.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat.

1 reference

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28 May 2018

Exogenous NGF affects cholinergic transmitter function and Y-maze behavior in aged Fischer 344 male rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Nerve growth factor and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates

1 reference

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

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28 May 2018

NGF improves spatial memory in aged rodents as a function of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Short-term memory in the rhesus monkey: disruption from the anti-cholinergic scopolamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

28 May 2018

Changes in brain cholinesterases in senile dementia of Alzheimer type.

1 reference

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28 May 2018

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

16 August 2018

AAV2/5-mediated NGF gene delivery protects septal cholinergic neurons following axotomy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

16 August 2018

Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons

1 reference

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16 August 2018

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

1 reference

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Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

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16 August 2018

Long-Term Neuronal Effects and Disposition of Ectopic preproNGF Gene Transfer into the Rat Septum

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16 August 2018

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1 reference

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16 August 2018

Cholinergic enhancement and increased selectivity of perceptual processing during working memory.

1 reference

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16 August 2018

Scopolamine alters rhesus monkey performance on a novel neuropsychological test battery.

1 reference

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16 August 2018

NGF content in the cerebral cortex of non-demented patients with amyloid-plaques and in symptomatic Alzheimer's disease.

1 reference

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16 August 2018

Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesion-induced degeneration

1 reference

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16 August 2018

Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease.

1 reference

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16 August 2018

Hyperplastic changes within the leptomeninges of the rat and monkey in response to chronic intracerebroventricular infusion of nerve growth factor

1 reference

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16 August 2018

Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease.

1 reference

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16 August 2018

Human nerve growth factor improves spatial memory in aged but not in young rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

16 August 2018

Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709503

16 August 2018

Rescue of lesioned septal cholinergic neurons by nerve growth factor: specificity and requirement for chronic treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Traffic at the intersection of neurotrophic factor signaling and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXPNEUROL.2008.03.004

1 reference

Europe PubMed Central

31 October 2017

1 reference

Europe PubMed Central

31 October 2017

1 reference

Europe PubMed Central

31 October 2017

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0 references

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