(Q42437014)

31 October 2017

title

RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha (English)

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31 October 2017

T T Giang Ho

1

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31 October 2017

Sofia D Merajver

2

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31 October 2017

Charles M Lapière

3

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31 October 2017

Betty V Nusgens

4

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31 October 2017

Christophe F Deroanne

5

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31 October 2017

language of work or name

English

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publication date

4 June 2008

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Journal of Biological Chemistry

31 October 2017

published in

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31 October 2017

volume

283

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31 October 2017

issue

31

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31 October 2017

page(s)

21588-21598

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Rho GTPases and their effector proteins

31 October 2017

cites work

1 reference

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Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP.

21 January 2018

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Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase

21 January 2018

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Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling

21 January 2018

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Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes

21 January 2018

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Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells

21 January 2018

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A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells

21 January 2018

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Mechanism of NADPH oxidase activation by the Rac/Rho-GDI complex

21 January 2018

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Disruption of RhoGDI and RhoA regulation by a Rac1 specificity switch mutant

21 January 2018

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21 January 2018

Rho proteins and cancer

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Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells

21 January 2018

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Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis

21 January 2018

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In vivo restoration of RhoB expression leads to ovarian tumor regression.

21 January 2018

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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

21 January 2018

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Cdc42 downregulates MMP-1 expression by inhibiting the ERK1/2 pathway

21 January 2018

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RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling

21 January 2018

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Rho GDP dissociation inhibitor protects cancer cells against drug-induced apoptosis

21 January 2018

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Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition

21 January 2018

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Hmg-CoA reductase inhibitor modulates monocyte-endothelial cell interaction under physiological flow conditions in vitro: involvement of Rho GTPase-dependent mechanism

21 January 2018

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Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 January 2018

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Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

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Isoprenylation of RhoB is necessary for its degradation. A novel determinant in the complex regulation of RhoB expression by the mevalonate pathway

21 January 2018

1 reference

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Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma

21 January 2018

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rhoB encoding a UV-inducible Ras-related small GTP-binding protein is regulated by GTPases of the Rho family and independent of JNK, ERK, and p38 MAP kinase

21 January 2018

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Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

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Cellular stability of Rho-GTPases glucosylated by Clostridium difficile toxin B.

21 January 2018

1 reference

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Upregulation of the immediate early gene product RhoB by exoenzyme C3 from Clostridium limosum and toxin B from Clostridium difficile

21 January 2018

1 reference

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Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

21 January 2018

1 reference

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Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710033200

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

21 January 2018

1 reference

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RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710033200

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710033200

Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710033200

RhoGDI: multiple functions in the regulation of Rho family GTPase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710033200

21 January 2018

Identifiers

DOI

10.1074/JBC.M710033200

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31 October 2017

1 reference