(Q42438728)

31 October 2017

Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk. (English)

1 reference

31 October 2017

0 references

Grzegorz Nalepa

14

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author name string

Karl Staser

1

1 reference

31 October 2017

Su-Jung Park

2

1 reference

31 October 2017

Steven D Rhodes

3

1 reference

31 October 2017

Yi Zeng

4

1 reference

31 October 2017

Yong Zheng He

5

1 reference

31 October 2017

Matthew A Shew

6

1 reference

31 October 2017

Jeffrey R Gehlhausen

7

1 reference

31 October 2017

Donna Cerabona

8

1 reference

31 October 2017

Keshav Menon

9

1 reference

31 October 2017

Shi Chen

10

1 reference

31 October 2017

Zejin Sun

11

1 reference

31 October 2017

Jin Yuan

12

1 reference

31 October 2017

David A Ingram

13

1 reference

31 October 2017

Feng-Chun Yang

15

1 reference

31 October 2017

D Wade Clapp

16

1 reference

31 October 2017

language of work or name

English

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publication date

10 December 2012

1 reference

Journal of Clinical Investigation

31 October 2017

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31 October 2017

123

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31 October 2017

1

1 reference

31 October 2017

329-334

1 reference

Constitutive MAP kinase activation in hematopoietic stem cells induces a myeloproliferative disorder

31 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

MAPK signaling pathways in the regulation of hematopoiesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Erk1/2 MAP kinases are required for epidermal G2/M progression

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Activation of mitogen-activated protein kinase kinase (MEK)/extracellular signal regulated kinase (ERK) signaling pathway is involved in myeloid lineage commitment

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Phosphorylation of C/EBPalpha inhibits granulopoiesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Neurofibromas in NF1: Schwann cell origin and role of tumor environment

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Nf1 and Gmcsf interact in myeloid leukemogenesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

The GTPase superfamily: a conserved switch for diverse cell functions

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

The role of erk1 and erk2 in multiple stages of T cell development.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533306

16 August 2018

Identifiers

DOI

10.1172/JCI66167

1 reference

31 October 2017

1 reference

31 October 2017

PubMed publication ID

23221339

1 reference