(Q42468036)

1 November 2017

The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis (English)

1 reference

Salvador family WW domain containing protein 1

1 November 2017

0 references

1 reference

GOA release 2020-03-11

author

Dae-Sik Lim

5

1 reference

1 November 2017

Miju Kim

1

1 reference

1 November 2017

Minchul Kim

2

1 reference

1 November 2017

Mi-Sun Lee

3

1 reference

1 November 2017

Cheol-Hee Kim

4

1 reference

1 November 2017

language of work or name

English

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publication date

4 November 2014

1 reference

1 November 2017

Nature Communications

1 reference

1 November 2017

5

1 reference

1 November 2017

5370

1 reference

https://scigraph.springernature.com/pub.10.1038/ncomms6370

1 November 2017

0 references

cites work

Ciliogenesis: building the cell's antenna

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Primary cilia regulate mTORC1 activity and cell size through Lkb1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The primary cilium as a cellular signaling center: lessons from disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

When cilia go bad: cilia defects and ciliopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Centriole maturation and transformation to basal body

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

HEF1-dependent Aurora A activation induces disassembly of the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Pitchfork regulates primary cilia disassembly and left-right asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The Hippo pathway and human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The Hippo pathway: regulators and regulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

MST1 limits the kinase activity of aurora B to promote stable kinetochore-microtubule attachment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Polarity proteins control ciliogenesis via kinesin motor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The ciliary transition zone: from morphology and molecules to medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

NPHP proteins: gatekeepers of the ciliary compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Targeted disruption of Nphp1 causes male infertility due to defects in the later steps of sperm morphogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

pVHL and GSK3beta are components of a primary cilium-maintenance signalling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

A crucial role of WW45 in developing epithelial tissues in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Cep97 and CP110 suppress a cilia assembly program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Primary cilia are lost in preinvasive and invasive prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Aurora A regulates prometaphase progression by inhibiting the ability of RASSF1A to suppress APC-Cdc20 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6370

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS6370

1 reference

1 November 2017

0 references

1 reference