(Q45354108)

13 December 2017

title

The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. (English)

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13 December 2017

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14

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13 December 2017

13

Thomas Benzing

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13 December 2017

6

Roman-Ulrich Müller

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13 December 2017

Sandra Habbig

1

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13 December 2017

Malte P Bartram

2

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13 December 2017

Josef G Sägmüller

3

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13 December 2017

Anabel Griessmann

4

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13 December 2017

Mareike Franke

5

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13 December 2017

Ricarda Schwarz

7

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13 December 2017

Martin Hoehne

8

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13 December 2017

Carsten Bergmann

9

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13 December 2017

Claudia Tessmer

10

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13 December 2017

H Christian Reinhardt

11

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13 December 2017

Volker Burst

12

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13 December 2017

publication date

1 October 2012

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13 December 2017

published in

Human Molecular Genetics

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13 December 2017

volume

21

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13 December 2017

issue

26

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13 December 2017

page(s)

5528-5538

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Clinical spectrum and pathogenesis of nephronophthisis

13 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Nephronophthisis: disease mechanisms of a ciliopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Hippo signaling in organ size control

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Coordinating developmental signaling: novel roles for the Hippo pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The hippo signaling pathway in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

TAZ is a novel oncogene in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

NEK8 mutations affect ciliary and centrosomal localization and may cause nephronophthisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The basal body gene, RPGRIP1L, is a candidate tumour suppressor gene in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The Nek8 protein kinase, mutated in the human cystic kidney disease nephronophthisis, is both activated and degraded during ciliogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Cystic kidney disease: the role of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The primary cilium: a signalling centre during vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Altered Hippo signalling in polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The ciliary protein Nek8/Nphp9 acts downstream of Inv/Nphp2 during pronephros morphogenesis and left-right establishment in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Continuous cultures of fused cells secreting antibody of predefined specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

21 January 2018

Identifiers

DOI

10.1093/HMG/DDS408

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13 December 2017

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