(Q42491304)

1 November 2017

High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)? (English)

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1 November 2017

T Crook

1

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1 November 2017

J M Nicholls

2

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1 November 2017

L Brooks

3

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1 November 2017

J O'Nions

4

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1 November 2017

M J Allday

5

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1 November 2017

language of work or name

English

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publication date

1 July 2000

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1 November 2017

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1 November 2017

19

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1 November 2017

30

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1 November 2017

3439-3444

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203656

1 November 2017

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cites work

Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

p53 mutations implicate sunlight in post-transplant skin cancer irrespective of human papillomavirus status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Association of Epstein-Barr virus infection with p53 protein accumulation but not bcl-2 protein in nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

P53 overexpression and Epstein-Barr virus infection in undifferentiated and squamous cell nasopharyngeal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Epstein-Barr virus infection and the pathogenesis of nasopharyngeal carcinoma: viral gene expression, tumour cell phenotype, and the role of the lymphoid stroma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Assessment of p53 expression in nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

7 January 2021

The CDKN2A (p16) gene and human cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

7 January 2021

Mechanisms of p16INK4A inactivation in non small-cell lung cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

7 January 2021

Association of p63 with proliferative potential in normal and neoplastic human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

7 January 2021

The p16INK4a/CDKN2A tumor suppressor and its relatives.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

7 January 2021

Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203656

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203656

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Dimensions Publication ID

1 November 2017

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1 reference