(Q42494705)

1 November 2017

title

Controversial role of mast cells in skin cancers (English)

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1 November 2017

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Giancarlo Marone

3

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Maria Rosaria Galdiero

object named as

Maria R Galdiero

2

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Gianni Marone

object named as

Gianni Marone

6

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Gilda Varricchi

1

object named as

Gilda Varricchi

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1 November 2017

author name string

Francescopaolo Granata

4

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1 November 2017

Francesco Borriello

5

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1 November 2017

publication date

15 June 2016

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1 November 2017

published in

Experimental Dermatology

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1 November 2017

volume

26

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1 November 2017

issue

1

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1 November 2017

page(s)

11-17

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Targeting epigenetic readers in cancer.

1 November 2017

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IgE and mast cells in allergic disease

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Role of superallergens in allergic disorders

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Immunopharmacological modulation of mast cells.

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A beneficial role for immunoglobulin E in host defense against honeybee venom

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Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity

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Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

21 January 2018

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Mast cells can enhance resistance to snake and honeybee venoms

21 January 2018

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Molecular mechanism of mast cell mediated innate defense against endothelin and snake venom sarafotoxin

21 January 2018

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Tumour angiogenesis and mast cell density in the prognostic assessment of colorectal carcinomas.

21 January 2018

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High density of tryptase-positive mast cells in human colorectal cancer: a poor prognostic factor related to protease-activated receptor 2 expression

21 January 2018

1 reference

Correlation between serum tryptase, mast cells positive to tryptase and microvascular density in colo-rectal cancer patients: possible biological-clinical significance

21 January 2018

1 reference

Prognostic significance of mast cell number and microvascular density for the survival of patients with primary colorectal cancer.

21 January 2018

1 reference

Mast cells play a protumorigenic role in primary cutaneous lymphoma

21 January 2018

1 reference

Mast cell positivity to tryptase correlates with metastatic lymph nodes in gastrointestinal cancer patients treated surgically

21 January 2018

1 reference

Expression of chymase-positive cells in gastric cancer and its correlation with the angiogenesis

21 January 2018

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Infiltrating mast cells correlate with angiogenesis in bone metastases from gastric cancer patients

21 January 2018

1 reference

Mast cell infiltration correlates with poor prognosis in Hodgkin's lymphoma

21 January 2018

1 reference

Prognostic influence of tumor-infiltrating mast cells in patients with follicular lymphoma treated with rituximab and CHOP.

21 January 2018

1 reference

Mast cells mediate malignant pleural effusion formation.

21 January 2018

1 reference

Neovascularisation, expression of fibroblast growth factor-2, and mast cells with tryptase activity increase simultaneously with pathological progression in human malignant melanoma

21 January 2018

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Tumor vascularity and tryptase-positive mast cells correlate with a poor prognosis in melanoma.

21 January 2018

1 reference

Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression

21 January 2018

1 reference

Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma.

21 January 2018

1 reference

Mast cells are novel independent prognostic markers in prostate cancer and represent a target for therapy

21 January 2018

1 reference

Mast cells have a protumorigenic role in human thyroid cancer

21 January 2018

1 reference

Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway.

21 January 2018

1 reference

Mast cells mobilize myeloid-derived suppressor cells and Treg cells in tumor microenvironment via IL-17 pathway in murine hepatocarcinoma model

21 January 2018

1 reference

Decreased susceptibility of mast cell-deficient Kit(W)/Kit(W-v) mice to the development of 1, 2-dimethylhydrazine-induced intestinal tumors

21 January 2018

1 reference

Mast cells are an essential hematopoietic component for polyp development

21 January 2018

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Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice

21 January 2018

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Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment.

21 January 2018

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SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

21 January 2018

1 reference

The critical role of mast cell-derived hypoxia-inducible factor-1α in human and mice melanoma growth

21 January 2018

1 reference

Immunoglobulin E induces VEGF production in mast cells and potentiates their pro-tumorigenic actions through a Fyn kinase-dependent mechanism.

21 January 2018

1 reference

Cutting edge: mast cells critically augment myeloid-derived suppressor cell activity.

21 January 2018

1 reference

SCF and TLR4 ligand cooperate to augment the tumor-promoting potential of mast cells

21 January 2018

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Dynamic mast cell-stromal cell interactions promote growth of pancreatic cancer

21 January 2018

1 reference

Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma

21 January 2018

1 reference

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors

21 January 2018

1 reference

Mast cell-derived angiopoietin-1 plays a critical role in the growth of plasma cell tumors

21 January 2018

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Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

21 January 2018

1 reference

HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells

21 January 2018

1 reference

A protective role of mast cells in intestinal tumorigenesis

21 January 2018

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A critical role for mast cells and mast cell-derived IL-6 in TLR2-mediated inhibition of tumor growth.

21 January 2018

1 reference

Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells

21 January 2018

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Mast cell targeting hampers prostate adenocarcinoma development but promotes the occurrence of highly malignant neuroendocrine cancers

21 January 2018

1 reference

Mast cells protect from skin tumor development and limit tumor growth during cutaneous de novo carcinogenesis in a Kit-dependent mouse model.

21 January 2018

1 reference

The presence of stromal mast cells identifies a subset of invasive breast cancers with a favorable prognosis

21 January 2018

1 reference

Mast cells and eosinophils in invasive breast carcinoma

21 January 2018

1 reference

Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases

21 January 2018

1 reference

Prognostic significance of cell infiltrations of immunosurveillance in colorectal cancer

21 January 2018

1 reference

Mast cells in cutaneous tumors: innocent bystander or maestro conductor?

21 January 2018

1 reference

Low numbers of tryptase+ and chymase+ mast cells associated with reduced survival and advanced tumor stage in melanoma

21 January 2018

1 reference

Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer.

21 January 2018

1 reference

Immunological microenvironment in prostate cancer: high mast cell densities are associated with favorable tumor characteristics and good prognosis

21 January 2018

1 reference

Mast cells: potential positive and negative roles in tumor biology.

21 January 2018

1 reference

Mast cells are dispensable for normal and activin-promoted wound healing and skin carcinogenesis

21 January 2018

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No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients

21 January 2018

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The significance and relationship between mast cells and tumour angiogenesis in non-small cell lung carcinoma.

21 January 2018

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Association of mast cells with microvessel density in renal cell carcinomas.

21 January 2018

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Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

21 January 2018

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Tryptase-chymase double-positive human mast cells express the eotaxin receptor CCR3 and are attracted by CCR3-binding chemokines

21 January 2018

1 reference

Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.

21 January 2018

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The chemokine receptor CXCR4 is expressed within the mast cell lineage and its ligand stromal cell-derived factor-1alpha acts as a mast cell chemotaxin

21 January 2018

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Chemotactic action of prostaglandin E2 on mouse mast cells acting via the PGE2 receptor 3.

21 January 2018

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Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors

21 January 2018

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Osteopontin is produced by mast cells and affects IgE-mediated degranulation and migration of mast cells

21 January 2018

1 reference

Tumor metabolism as modulator of immune response and tumor progression

21 January 2018

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Mast cell survival and mediator secretion in response to hypoxia

21 January 2018

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HIF-1alpha is up-regulated in activated mast cells by a process that involves calcineurin and NFAT.

21 January 2018

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Adenosine release from stimulated mast cells

21 January 2018

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Production of vascular endothelial growth factors from human lung macrophages induced by group IIA and group X secreted phospholipases A2

21 January 2018

1 reference

Tumor-Associated Mast Cells in Thyroid Cancer

21 January 2018

1 reference

Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses.

21 January 2018

1 reference

Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation

21 January 2018

1 reference

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation

21 January 2018

1 reference

Dermal mast cells affect the development of sunlight-induced skin tumours.

21 January 2018

1 reference

Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis

21 January 2018

1 reference

Dermal mast cells determine susceptibility to ultraviolet B-induced systemic suppression of contact hypersensitivity responses in mice

21 January 2018

1 reference

Mast cells and cutaneous malignancies

21 January 2018

1 reference

Melanoma. An ultrastructural study of the host inflammatory and vascular responses

21 January 2018

1 reference

A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma

21 January 2018

1 reference

TIM-3 is expressed in melanoma cells and is upregulated in TGF-beta stimulated mast cells

21 January 2018

1 reference

Emerging Tim-3 functions in antimicrobial and tumor immunity

21 January 2018

1 reference

Mast cell-derived TNF-α and histamine modify IL-6 and IL-8 expression and release from cutaneous tumor cells

21 January 2018

1 reference

Mast cells and dendritic cells in basal cell carcinoma stroma

21 January 2018

1 reference

Communications: high dermal mast cell prevalence is a predisposing factor for basal cell carcinoma in humans

21 January 2018

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Increased dermal mast cell prevalence and susceptibility to development of basal cell carcinoma in humans

21 January 2018

1 reference

Mast cells in basal cell carcinoma express VEGF, IL-8 and RANTES.

21 January 2018

1 reference

Increase in CD30 ligand/CD153 and TNF-alpha expressing mast cells in basal cell carcinoma

21 January 2018

1 reference

Mast cells express functional CD30 ligand and are the predominant CD30L-positive cells in Hodgkin's disease.

21 January 2018

1 reference

Primary cutaneous lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

21 January 2018

1 reference

Pathogenesis of infantile haemangioma.

21 January 2018

1 reference

Cellular markers that distinguish the phases of hemangioma during infancy and childhood

21 January 2018

1 reference

New models for analyzing mast cell functions in vivo

21 January 2018

1 reference

Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.

21 January 2018

1 reference

Tryptase Mast Cells in Malignant Pleural Mesothelioma as an Independent Favorable Prognostic Factor

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/EXD.13107

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1 November 2017

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