(Q42505499)

1 November 2017

title

Ric-8A, an activator protein of Gαi, controls mammalian epithelial cell polarity for tight junction assembly and cystogenesis (English)

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1 November 2017

Kanako Chishiki

1

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1 November 2017

Sachiko Kamakura

series ordinal

2

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1 November 2017

Junya Hayase

series ordinal

3

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1 November 2017

Hideki Sumimoto

series ordinal

4

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1 November 2017

publication date

10 February 2017

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1 November 2017

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1 November 2017

volume

22

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1 November 2017

issue

3

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1 November 2017

page(s)

293-309

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Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.

1 November 2017

cites work

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Resistance to inhibitors of cholinesterase (Ric)-8A and Gαi contribute to cytokinesis abscission by controlling vacuolar protein-sorting (Vps)34 activity

21 January 2018

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From cells to organs: building polarized tissue.

21 January 2018

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Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits

21 January 2018

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Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

21 January 2018

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Ubiquitination of the heterotrimeric G protein α subunits Gαi2 and Gαq is prevented by the guanine nucleotide exchange factor Ric-8A.

21 January 2018

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Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division.

21 January 2018

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Apical surface formation in MDCK cells: regulation by the serine/threonine kinase EMK1.

21 January 2018

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Molecular regulation of lumen morphogenesis.

21 January 2018

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Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis

21 January 2018

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Midbody: from cellular junk to regulator of cell polarity and cell fate

21 January 2018

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Polarity proteins regulate mammalian cell-cell junctions and cancer pathogenesis

21 January 2018

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Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association

21 January 2018

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Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins

21 January 2018

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The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells.

21 January 2018

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A multicellular view of cytokinesis in epithelial tissue

21 January 2018

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Ric-8: different cellular roles for a heterotrimeric G-protein GEF.

21 January 2018

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Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells

21 January 2018

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Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment

21 January 2018

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Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.

21 January 2018

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Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

21 January 2018

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The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway

21 January 2018

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Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

21 January 2018

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Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase

21 January 2018

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Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.

21 January 2018

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21 January 2018

Epithelial homeostasis

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PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.

21 January 2018

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Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis

21 January 2018

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Functional analysis of tight junctions

21 January 2018

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The RGS14 GoLoco domain discriminates among Galphai isoforms

21 January 2018

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The polarized distribution of an apical cell surface glycoprotein is maintained by interactions with the cytoskeleton of Madin-Darby canine kidney cells

21 January 2018

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Heterotrimeric G protein activation by G-protein-coupled receptors

21 January 2018

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Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.

21 January 2018

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Mechanisms of apical-basal axis orientation and epithelial lumen positioning.

21 January 2018

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The G protein α chaperone Ric-8 as a potential therapeutic target

21 January 2018

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Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

21 January 2018

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Pertussis toxin induces structural changes in G alpha proteins independently of ADP-ribosylation

21 January 2018

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Organization and execution of the epithelial polarity programme

21 January 2018

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The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis.

21 January 2018

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Involvement of Galphai2 in the maintenance and biogenesis of epithelial cell tight junctions

21 January 2018

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Regulation of epithelial cell polarity by PAR-3 depends on Girdin transcription and Girdin-Gαi3 signaling.

21 January 2018

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Accessory proteins for G proteins: partners in signaling.

21 January 2018

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Cell polarity in eggs and epithelia: parallels and diversity

21 January 2018

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The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1.

21 January 2018

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Modulation of the expression of an apical plasma membrane protein of Madin-Darby canine kidney epithelial cells: cell-cell interactions control the appearance of a novel intracellular storage compartment

21 January 2018

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Exocytosis of vacuolar apical compartment (VAC): a cell-cell contact controlled mechanism for the establishment of the apical plasma membrane domain in epithelial cells

21 January 2018

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Return of the GDI: the GoLoco motif in cell division.

21 January 2018

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A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics

21 January 2018

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Asymmetric cell divisions promote Notch-dependent epidermal differentiation

21 January 2018

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Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants

21 January 2018

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Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle

21 January 2018

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Tre1 GPCR signaling orients stem cell divisions in the Drosophila central nervous system

21 January 2018

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Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)

21 January 2018

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LGN regulates mitotic spindle orientation during epithelial morphogenesis

21 January 2018

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Tight junctions: from simple barriers to multifunctional molecular gates

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/GTC.12477

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1 November 2017

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