(Q42508941)

English

Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells

scientific article published on 2 July 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

esophageal cancer

1 reference

based on heuristic

inferred from title

16

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

17

object named as

Susan E Bates

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

author name string

Mary Zhang

1

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Aarti Mathur

2

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Yuwei Zhang

3

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Sichuan Xi

4

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Scott Atay

5

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Julie A Hong

6

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Nicole Datrice

7

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Europe PubMed Central

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2 July 2019

http://europepmc.org/abstract/PMC/6261440

Trevor Upham

8

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2 July 2019

http://europepmc.org/abstract/PMC/6261440

Clinton D Kemp

9

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Europe PubMed Central

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2 July 2019

http://europepmc.org/abstract/PMC/6261440

R Taylor Ripley

10

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Gordon Wiegand

11

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Itzak Avital

12

1 reference

Europe PubMed Central

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2 July 2019

http://europepmc.org/abstract/PMC/6261440

Patricia Fetsch

13

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Haresh Mani

14

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Europe PubMed Central

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2 July 2019

http://europepmc.org/abstract/PMC/6261440

Daniel Zlott

15

1 reference

Europe PubMed Central

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2 July 2019

http://europepmc.org/abstract/PMC/6261440

Xinmin Li

18

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Europe PubMed Central

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2 July 2019

http://europepmc.org/abstract/PMC/6261440

Mahadev Rao

19

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

David S Schrump

20

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

language of work or name

0 references

publication date

2 July 2012

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

72

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

16

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

4178-4192

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Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

Influence of smoking status on treatment outcomes after post-operative radiation therapy for non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cigarette smoking and risk of lung metastasis from esophageal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic and toxic effects of mithramycin during tumor therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: implications for adoptive immunotherapy of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictors of major morbidity and mortality after esophagectomy for esophageal cancer: a Society of Thoracic Surgeons General Thoracic Surgery Database risk adjustment model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive expression of the ATP-binding cassette transporter ABCG2 enhances the growth potential of early human hematopoietic progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STS database risk models: predictors of mortality and major morbidity for lung cancer resection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pack-years of cigarette smoking as a prognostic factor in patients with stage IIIB/IV nonsmall cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cell gene expression changes induced specifically by mutated K-ras.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt signalling and cancer stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MITHRAMYCIN IN THE TREATMENT OF DISSEMINATED CANCER

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCG2: a potential marker of stem cells and novel target in stem cell and cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smoking-attributable mortality, years of potential life lost, and productivity losses--United States, 2000-2004

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sp transcription factor family and its role in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of antioxidant enzymes upregulates aryl hydrocarbon receptor expression via increased Sp1 DNA-binding activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCG2 expression is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of ABCG2 (BCRP) Is Regulated by Nrf2 in Cancer Cells That Confers Side Population and Chemoresistance Phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional networks in epithelial-mesenchymal transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of continued tobacco use during treatment of lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Sp1-dependent transcription and antitumor activity of the new aureolic acid analogues mithramycin SDK and SK in human ovarian cancer xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tobacco and the escalating global cancer burden

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies with tritiated mithramycin in C3H mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heavy smoking history interacts with chemoradiotherapy for esophageal cancer prognosis: a retrospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of ABCG2 by romidepsin via the aryl hydrocarbon receptor pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive AhR activation leads to concomitant ABCG2-mediated multidrug resistance in cisplatin-resistant esophageal carcinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The combination of stem cell markers CD133 and ABCG2 predicts relapse in stage I non-small cell lung carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22751465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-11-3983

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 July 2019

http://europepmc.org/abstract/PMC/6261440

ResearchGate publication ID

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