(Q42514518)

1 November 2017

title

The GTP-binding protein Rac does not couple PI 3-kinase to insulin-stimulated glucose transport in adipocytes (English)

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1 November 2017

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Marcusohn J

1

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1 November 2017

Isakoff SJ

2

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1 November 2017

Rose E

3

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1 November 2017

Symons M

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1 November 2017

Skolnik EY

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1 November 2017

language of work or name

English

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publication date

1 November 1995

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1 November 2017

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1 November 2017

volume

5

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1 November 2017

issue

11

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1 November 2017

page(s)

1296-1302

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Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity

1 November 2017

cites work

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7 January 2021

Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4.

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7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

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7 January 2021

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

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7 January 2021

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

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PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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Phosphoinositide kinases

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7 January 2021

Oncogenes and signal transduction

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Lipid second messengers

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Intracellular signalling. PI 3-kinase puts GTP on the Rac

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7 January 2021

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

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7 January 2021

The small GTPases Rac and Rho as regulators of secretion in mast cells

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Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase.

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Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

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7 January 2021

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

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7 January 2021

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

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7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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7 January 2021

An essential role for Rac in Ras transformation

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7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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7 January 2021

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

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7 January 2021

The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake

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7 January 2021

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

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7 January 2021

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7 January 2021

Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells

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7 January 2021

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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7 January 2021

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

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7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

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7 January 2021

Insulin-mediated translocation of glucose transporters from intracellular membranes to plasma membranes: sole mechanism of stimulation of glucose transport in L6 muscle cells

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7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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7 January 2021

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Identifiers

DOI

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1 November 2017

1 reference