(Q42520354)

2 July 2019

title

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox (English)

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2 July 2019

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9

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2 July 2019

Michael Aschner

12

object named as

Michael Aschner

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2 July 2019

Rodrigo B. Leal

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author name string

Filipe M Gonçalves

5

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2 July 2019

Daniela Z Pedro

6

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2 July 2019

Samantha C Lopes

7

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2 July 2019

Célso Pilati

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2 July 2019

Keith M Erikson

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2 July 2019

publication date

6 February 2013

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2 July 2019

published in

Archives of Toxicology

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2 July 2019

volume

87

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2 July 2019

issue

7

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2 July 2019

page(s)

1231-1244

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2 July 2019

https://scigraph.springernature.com/pub.10.1007/s00204-013-1017-5

exact match

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In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function

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Manganese modulation of MAPK pathways: effects on upstream mitogen activated protein kinase kinases and mitogen activated kinase phosphatase-1 in microglial cells

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Vitamin A supplementation induces a prooxidative state in the striatum and impairs locomotory and exploratory activity of adult rats

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A manganese-enhanced diet alters brain metals and transporters in the developing rat.

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Manganese activates the mitochondrial apoptotic pathway in rat astrocytes by modulating the expression of proteins of the Bcl-2 family.

21 January 2018

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Rodent Brain Growth Stages: An Analytical Review

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury

21 January 2018

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Sub-cellular localization of manganese in the basal ganglia of normal and manganese-treated rats An electron spectroscopy imaging and electron energy-loss spectroscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Developmental exposure to manganese increases adult susceptibility to inflammatory activation of glia and neuronal protein nitration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Age-dependent susceptibility to manganese-induced neurological dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Learning and memory functions of the Basal Ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Induction of oxidative stress and inflammatory cytokines by manganese chloride in cultured T98G cells, human brain glioblastoma cell line

21 January 2018

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The neuropathology of manganese-induced Parkinsonism

21 January 2018

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A simplification of the protein assay method of Lowry et al. which is more generally applicable

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Individual differences in the effects of cannabinoids on motor activity, dopaminergic activity and DARPP-32 phosphorylation in distinct regions of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Exposure of C6 glioma cells to Pb(II) increases the phosphorylation of p38(MAPK) and JNK1/2 but not of ERK1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Molecular mechanism of manganese exposure-induced dopaminergic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Developing brain as a target of toxicity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Are there common biochemical and molecular mechanisms controlling manganism and parkisonism

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Iron interactions and other biological reactions mediating the physiological and toxic actions of manganese

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Effects of chronic manganese exposure on working memory in non-human primates

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Manganese-mediated up-regulation of HIF-1alpha protein in Hep2 human laryngeal epithelial cells via activation of the family of MAPKs

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Temporal parenteral nutrition in children causing t1 shortening in the anterior pituitary gland and globus pallidus.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

DARPP-32: an integrator of neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Mitochondrial-mediated apoptosis in neural stem cells exposed to manganese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

MAPK cascade signalling and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Developmental and regional changes in the neurochemical profile of the rat brain determined by in vivo 1H NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Chronic manganese poisoning: a neuropathological study with determination of manganese distribution in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Physiologically based pharmacokinetic modeling of fetal and neonatal manganese exposure in humans: describing manganese homeostasis during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

In vitro effect of manganese chloride exposure on reactive oxygen species generation and respiratory chain complexes activities of mitochondria isolated from rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

In vitro effect of manganese chloride exposure on energy metabolism and oxidative damage of mitochondria isolated from rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Brain barrier systems: a new frontier in metal neurotoxicological research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

9-Benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Maternal and early life exposure to manganese in rural Bangladesh

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-013-1017-5

Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade

21 January 2018

1 reference

12 December 2020

Mammalian MAP kinase signalling cascades

1 reference

12 December 2020

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12 December 2020

Glutamate/aspartate transporter (GLAST), taurine transporter and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate or manganese sulfate

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12 December 2020

Protein measurement with the Folin phenol reagent

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12 December 2020

Advances in protein kinase B signalling: AKTion on multiple fronts

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12 December 2020

Neurodegenerative and physiological actions of c-Jun N-terminal kinases in the mammalian brain

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12 December 2020

Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons

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12 December 2020

The basal ganglia: learning new tricks and loving it.

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12 December 2020

Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia

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12 December 2020

Regulation of DARPP-32 phosphorylation by Δ9-tetrahydrocannabinol

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12 December 2020

Manganese exposure, essentiality & toxicity.

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12 December 2020

Blockade of adenosine A2A receptors downregulates DARPP-32 but increases ERK1/2 activity in striatum of dopamine deficient "weaver" mouse

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12 December 2020

Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat.

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12 December 2020

The internal state of medium spiny neurons varies in response to different input signals

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12 December 2020

Regional variations in protein phosphorylating activity in rat brain studied in micro-slices labeled with [32P]phosphate

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12 December 2020

The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells.

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12 December 2020

Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways.

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12 December 2020

A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions

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12 December 2020

Effect of treatment with mercury chloride and lead acetate during the second stage of rapid postnatal brain growth on delta-aminolevulinic acid dehydratase (ALA-D) activity in brain, liver, kidney and blood of suckling rats

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12 December 2020

Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress

1 reference

12 December 2020

10.1007/S00204-013-1017-5

Identifiers

DOI

1 reference

2 July 2019

PMC publication ID

6543098

1 reference

2 July 2019

PubMed publication ID

23385959

1 reference

2 July 2019