(Q42525438)

1 November 2017

Constitutive activity of the cannabinoid CB1 receptor regulates the function of co-expressed Mu opioid receptors (English)

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1 November 2017

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Meritxell Canals

1

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author name string

Graeme Milligan

series ordinal

2

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PubMed ID

18319252

1 November 2017

language of work or name

English

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publication date

4 March 2008

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Journal of Biological Chemistry

1 November 2017

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1 November 2017

283

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1 November 2017

17

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1 November 2017

11424-11434

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Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse

1 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Opioid and cannabinoid receptor inhibition of adenylyl cyclase in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Pharmacology of cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Molecular mechanisms of opiate receptor coupling to G proteins and effector systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

CB1-cannabinoid and mu-opioid receptor co-localization on postsynaptic target in the rat dorsal horn

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Opioid and cannabinoid receptors: friends with benefits or just close friends?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Interactions between CB1 cannabinoid and mu opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Motivational effects of cannabinoids and opioids on food reinforcement depend on simultaneous activation of cannabinoid and opioid systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

G protein-coupled receptor dimerisation: molecular basis and relevance to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Interactions between the Mas-related receptors MrgD and MrgE alter signalling and trafficking of MrgD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional im

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Enhanced degradation of the phosphoinositidase C-linked guanine-nucleotide-binding protein Gq alpha/G11 alpha following activation of the human M1 muscarinic acetylcholine receptor expressed in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Identification of two distinct isoforms of the guanine nucleotide binding protein G0 in neuroblastoma X glioma hybrid cells: independent regulation during cyclic AMP-induced differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

The alpha1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Suppression of feeding, drinking, and locomotion by a putative cannabinoid receptor 'silent antagonist'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB1 and CB2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Inverse agonism and neutral antagonism at cannabinoid CB1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Constitutive activity and inverse agonists of G protein-coupled receptors: a current perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

The role of diacylglycerol lipase in constitutive and angiotensin AT1 receptor-stimulated cannabinoid CB1 receptor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Principles: extending the utility of [35S]GTP gamma S binding assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Involvement of the carboxyl terminus of the third intracellular loop of the cannabinoid CB1 receptor in constitutive activation of Gs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Specificity and functional applications of antipeptide antisera which identify G-protein alpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Identification of a serotonin/glutamate receptor complex implicated in psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Constitutive activation drives compartment-selective endocytosis and axonal targeting of type 1 cannabinoid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

An essential role for constitutive endocytosis, but not activity, in the axonal targeting of the CB1 cannabinoid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Virally encoded 7TM receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Efficacy as a vector: the relative prevalence and paucity of inverse agonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Inverse agonism: from curiosity to accepted dogma, but is it clinically relevant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Versatility of GPCR recognition by drugs: from biological implications to therapeutic relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

The evasive nature of drug efficacy: implications for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Agonist activation of p42 and p44 mitogen-activated protein kinases following expression of the mouse delta opioid receptor in Rat-1 fibroblasts: effects of receptor expression levels and comparisons with G-protein activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Beta-arrestins and cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Mu opioid receptor activation of ERK1/2 is GRK3 and arrestin dependent in striatal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

Extracellular signal-regulated kinase 1/2-mediated transcriptional regulation of G-protein-coupled receptor kinase 3 expression in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710300200

21 January 2018

Identifiers

DOI

10.1074/JBC.M710300200

1 reference

1 November 2017

1 reference

PubMed ID

18319252