(Q42546429)

English

Increased eIF2alpha phosphorylation attenuates replication of herpes simplex virus 2 vhs mutants in mouse embryonic fibroblasts and correlates with reduced accumulation of the PKR antagonist ICP34.5.

scientific article published on 8 July 2009

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scholarly article

1 reference

Europe PubMed Central

2 November 2017

Increased eIF2alpha phosphorylation attenuates replication of herpes simplex virus 2 vhs mutants in mouse embryonic fibroblasts and correlates with reduced accumulation of the PKR antagonist ICP34.5. (English)

1 reference

Europe PubMed Central

2 November 2017

phosphorylation

1 reference

based on heuristic

inferred from title

Kristine M Wylie

1

object named as

Kristine M Wylie

1 reference

Europe PubMed Central

2 November 2017

author name string

Jane E Schrimpf

2

1 reference

Europe PubMed Central

2 November 2017

Lynda A Morrison

3

1 reference

Europe PubMed Central

2 November 2017

language of work or name

0 references

publication date

8 July 2009

1 reference

Europe PubMed Central

2 November 2017

Journal of Virology

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Europe PubMed Central

2 November 2017

83

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Europe PubMed Central

2 November 2017

18

1 reference

Europe PubMed Central

2 November 2017

9151-9162

1 reference

Europe PubMed Central

2 November 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2738226/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Control of TANK-binding kinase 1-mediated signaling by the gamma(1)34.5 protein of herpes simplex virus 1

1 reference

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An acutely and latently expressed herpes simplex virus 2 viral microRNA inhibits expression of ICP34.5, a viral neurovirulence factor

1 reference

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1 reference

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Herpes simplex virus virion host shutoff attenuates establishment of the antiviral state

1 reference

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Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice

1 reference

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HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein

1 reference

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Analysis of the role of autophagy in replication of herpes simplex virus in cell culture

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1 reference

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1 reference

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Regulation of eIF2alpha phosphorylation by different functions that act during discrete phases in the herpes simplex virus type 1 life cycle

1 reference

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Dephosphorylation of eIF-2alpha mediated by the gamma(1)34.5 protein of herpes simplex virus type 1 is required for viral response to interferon but is not sufficient for efficient viral replication

1 reference

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Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo

1 reference

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In vivo replication of an ICP34.5 second-site suppressor mutant following corneal infection correlates with in vitro regulation of eIF2 alpha phosphorylation

1 reference

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Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication

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The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

1 reference

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The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

1 reference

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Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2.

1 reference

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Oncogenic transformation of hamster cells after exposure to herpes simplex virus type 2.

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A mutant of herpes simplex virus type 1 exhibits increased stability of immediate-early (alpha) mRNAs

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On the control of immediate early (alpha) mRNA survival in cells infected with herpes simplex virus

1 reference

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Herpes simplex virus virion host shutoff function

1 reference

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Control of mRNA stability by the virion host shutoff function of herpes simplex virus

1 reference

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Mechanism and regulation of eukaryotic protein synthesis

1 reference

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The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

1 reference

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Herpes simplex virus 2 virion host shutoff protein interferes with type I interferon production and responsiveness

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16 August 2018

Herpes simplex virus vhs protein.

1 reference

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Early and delayed shut-off of host protein synthesis in cells infected with herpes simplex virus

1 reference

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16 August 2018

Identifiers

10.1128/JVI.00886-09

1 reference

Europe PubMed Central

2 November 2017

1 reference

Europe PubMed Central

2 November 2017

1 reference

Europe PubMed Central

2 November 2017

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