(Q42570141)

English

BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines

scientific article published on 6 January 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines (English)

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Nicholas W Morrell

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Nicholas W Morrell

10

0 references

author name string

Rachel J Davies

1

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Alan M Holmes

2

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

John Deighton

3

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Lu Long

4

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Xudong Yang

5

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Lucy Barker

6

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Christoph Walker

7

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

David C Budd

8

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Paul D Upton

9

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

publication date

6 January 2012

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

302

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

6

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

L604-15

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Rho-kinase regulates thrombin-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

The value of blocking IL-6 outside of rheumatoid arthritis: current perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Interleukin-6 as a potential therapeutic target for pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Non-Smad pathways in TGF-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Molecular mechanisms of pulmonary arterial hypertension: role of mutations in the bone morphogenetic protein type II receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Molecular pathogenesis of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Cellular and molecular pathobiology of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

TGF-beta signaling and the fibrotic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Inflammation in pulmonary arterial hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Transforming growth factor-beta1 induces interleukin-6 expression via activating protein-1 consisting of JunD homodimers in primary human lung fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

NF-kappa B subunit-specific regulation of the interleukin-8 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

28 May 2018

Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Role for interleukin-6 in COPD-related pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by mo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Increased plasma monocyte chemoattractant protein-1 level in idiopathic pulmonary arterial hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Transforming growth factor-beta1 inhibition of vascular smooth muscle cell activation is mediated via Smad3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cells through the synergistic collaboration of the Smad2, p38-NF-kappaB, JNK, and Ras signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311534

16 August 2018

Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00309.2011

21 January 2018

Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00309.2011

21 January 2018

Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth muscle via AT1 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 Stimulates Proliferation of Cultured Vascular Smooth Muscle Cells Independently of Interleukin-1β

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium channel blockers activate the interleukin-6 gene via the transcription factors NF-IL6 and NF-kappaB in primary human vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of transforming growth factor-beta in biological material using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocrotaline induces interleukin-6 mRNA expression in rat lungs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary hypertension in rats. 2. Role of interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of novel pathway regulation during myogenic differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

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based on heuristic

inferred from PubMed ID database lookup

Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22227206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPLUNG.00309.2011

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

ResearchGate publication ID

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