(Q42572387)

English

Topological analysis of HIV-1 glycoproteins expressed in situ on virus surfaces reveals tighter packing but greater conformational flexibility than for soluble gp120.

scientific article published on 5 June 2013

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scholarly article

1 reference

Europe PubMed Central

2 November 2017

Topological analysis of HIV-1 glycoproteins expressed in situ on virus surfaces reveals tighter packing but greater conformational flexibility than for soluble gp120. (English)

1 reference

Europe PubMed Central

2 November 2017

author name string

Tommy Tong

1

1 reference

Europe PubMed Central

2 November 2017

Keiko Osawa

2

1 reference

Europe PubMed Central

2 November 2017

James E Robinson

3

1 reference

Europe PubMed Central

2 November 2017

Ema T Crooks

4

1 reference

Europe PubMed Central

2 November 2017

James M Binley

5

1 reference

Europe PubMed Central

2 November 2017

language of work or name

0 references

publication date

5 June 2013

1 reference

Europe PubMed Central

2 November 2017

Journal of Virology

1 reference

Europe PubMed Central

2 November 2017

87

1 reference

Europe PubMed Central

2 November 2017

16

1 reference

Europe PubMed Central

2 November 2017

9233-9249

1 reference

Europe PubMed Central

2 November 2017

Inhibition of the HIV-1 spike by single-PG9/16-antibody binding suggests a coordinated-activation model for its three protomeric units

1 reference

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1 reference

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1 reference

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Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

1 reference

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1 reference

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HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins

1 reference

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28 May 2018

Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer

1 reference

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Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

1 reference

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1 reference

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28 May 2018

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1 reference

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28 May 2018

PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.

1 reference

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28 May 2018

HIV-1 virus-like particles bearing pure env trimers expose neutralizing epitopes but occlude nonneutralizing epitopes

1 reference

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HIV-1 neutralization coverage is improved by combining monoclonal antibodies that target independent epitopes

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HIV vaccine development at the turn of the 21st century

1 reference

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The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.

1 reference

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28 May 2018

Broad neutralization coverage of HIV by multiple highly potent antibodies

1 reference

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28 May 2018

Functional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1)

1 reference

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Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01.

1 reference

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Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

1 reference

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28 May 2018

Direct antibody access to the HIV-1 membrane-proximal external region positively correlates with neutralization sensitivity

1 reference

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28 May 2018

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

1 reference

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Enzyme digests eliminate nonfunctional Env from HIV-1 particle surfaces, leaving native Env trimers intact and viral infectivity unaffected

1 reference

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28 May 2018

MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1.

1 reference

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28 May 2018

Antibody epitope exposure and neutralization of HIV-1.

1 reference

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28 May 2018

Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

1 reference

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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

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28 May 2018

Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells.

1 reference

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28 May 2018

Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.

1 reference

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28 May 2018

GP41-specific antibody blocks cell-free HIV type 1 transcytosis through human rectal mucosa and model colonic epithelium.

1 reference

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In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1

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28 May 2018

The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120.

1 reference

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

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Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia

1 reference

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28 May 2018

Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity

1 reference

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HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

1 reference

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In vivo alteration of humoral responses to HIV-1 envelope glycoprotein gp120 by antibodies to the CD4-binding site of gp120.

1 reference

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28 May 2018

A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.

1 reference

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28 May 2018

Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positio

1 reference

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Evaluation of passively transferred, nonneutralizing antibody-dependent cellular cytotoxicity-mediating IgG in protection of neonatal rhesus macaques against oral SIVmac251 challenge.

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Characterizing anti-HIV monoclonal antibodies and immune sera by defining the mechanism of neutralization.

1 reference

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Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

1 reference

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Antigenic conservation and immunogenicity of the HIV coreceptor binding site

1 reference

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Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

1 reference

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Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage.

1 reference

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28 May 2018

The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection

1 reference

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28 May 2018

The v3 loop is accessible on the surface of most human immunodeficiency virus type 1 primary isolates and serves as a neutralization epitope.

1 reference

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28 May 2018

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

1 reference

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Redox-Triggered Infection by Disulfide-Shackled Human Immunodeficiency Virus Type 1 Pseudovirions

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28 May 2018

Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site

1 reference

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28 May 2018

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

1 reference

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Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies

1 reference

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Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion

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Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades.

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Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human Ig loci

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28 May 2018

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

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28 May 2018

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

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Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies.

1 reference

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Antigenic properties of the human immunodeficiency virus envelope during cell-cell fusion

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Additive Effects Characterize the Interaction of Antibodies Involved in Neutralization of the Primary Dualtropic Human Immunodeficiency Virus Type 1 Isolate 89.6

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Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

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Association of structural changes in the V2 and V3 loops of the gp120 envelope glycoprotein with acquisition of neutralization resistance in a simian-human immunodeficiency virus passaged in vivo

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Immunoreactivity of intact virions of human immunodeficiency virus type 1 (HIV-1) reveals the existence of fewer HIV-1 immunotypes than genotypes

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The human immunodeficiency virus type 1 gp120 V2 domain mediates gp41-independent intersubunit contacts

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A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

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Minimal incidence of serum antibodies reactive with intact primary isolate virions in human immunodeficiency virus type 1-infected individuals

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Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.

1 reference

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Synergistic neutralization of simian-human immunodeficiency virus SHIV-vpu+ by triple and quadruple combinations of human monoclonal antibodies and high-titer anti-human immunodeficiency virus type 1 immunoglobulins

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28 May 2018

Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein.

1 reference

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28 May 2018

Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex

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28 May 2018

Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.

1 reference

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Functional activities of 20 human immunodeficiency virus type 1 (HIV-1)-specific human monoclonal antibodies.

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Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

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28 May 2018

Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1

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28 May 2018

Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1.

1 reference

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28 May 2018

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28 May 2018

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28 May 2018

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

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28 May 2018

Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer

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28 May 2018

Epitope exposure on functional, oligomeric HIV-1 gp41 molecules

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28 May 2018

Immunization with a soluble CD4-gp120 complex preferentially induces neutralizing anti-human immunodeficiency virus type 1 antibodies directed to conformation-dependent epitopes of gp120.

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28 May 2018

Synergistic neutralization of human immunodeficiency virus type 1 by combinations of human monoclonal antibodies

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28 May 2018

Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies

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Generation and characterization of monoclonal antibodies to the putative CD4-binding domain of human immunodeficiency virus type 1 gp120.

1 reference

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28 May 2018

Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein

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28 May 2018

Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754051

28 May 2018

Inhibition of viral replication by monoclonal antibodies directed against human immunodeficiency virus gp120

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754051

28 May 2018

Native HIV type 1 virion surface structures: relationships between antibody binding and neutralization or lessons from the viral capture assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754051

16 August 2018

Potent neutralization of primary human immunodeficiency virus clade C isolates with a synergistic combination of human monoclonal antibodies raised against clade B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754051

16 August 2018

gp41: HIV's shy protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754051

1 December 2018

Interactions of human antibodies, epitope exposure, antibody binding and neutralization of primary isolate HIV-1 virions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23740975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base

1 reference

https://pubmed.ncbi.nlm.nih.gov/23740975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergy between human monoclonal antibodies to HIV extends their effective biologic activity against homologous and divergent strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/23740975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/23740975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of antibodies that inhibit HIV gp120 antigen processing and presentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23740975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01145-13

1 reference

Europe PubMed Central

2 November 2017

1 reference

Europe PubMed Central

2 November 2017

1 reference

Europe PubMed Central

2 November 2017

ResearchGate publication ID

0 references

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