(Q42588518)

English

Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase

scientific article published on 28 December 2010

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scholarly article

1 reference

Europe PubMed Central

3 November 2017

Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase (English)

1 reference

Europe PubMed Central

3 November 2017

Andrea Pellagatti

18

1 reference

Europe PubMed Central

3 November 2017

Jacqueline Boultwood

19

1 reference

Europe PubMed Central

3 November 2017

Melissa Fazzari

object named as

Melissa Fazzari

6

0 references

object named as

Alan List

25

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Tushar D Bhagat

3

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Tushar Bhagat

1 reference

Europe PubMed Central

3 November 2017

21

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Ulrich Steidl

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Europe PubMed Central

3 November 2017

7

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Davendra Sohal

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Europe PubMed Central

3 November 2017

Cristina Alencar

4

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Cristina Alencar

1 reference

Europe PubMed Central

3 November 2017

Christine M McMahon

2

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Christine McMahon

1 reference

Europe PubMed Central

3 November 2017

Leonidas C Platanias

20

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Leonidas C Platanias

1 reference

Europe PubMed Central

3 November 2017

Amittha Wickrema

13

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Amittha Wickrema

1 reference

Europe PubMed Central

3 November 2017

Christoph Heuck

8

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Christoph Heuck

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3 November 2017

16

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Lubomir Sokol

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3 November 2017

Krishna Gundabolu

9

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Krishna Gundabolu

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3 November 2017

Ioannis Mantzaris

17

object named as

Ioannis Mantzaris

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3 November 2017

26

object named as

Markus Bitzer

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3 November 2017

author name string

Li Zhou

1

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Europe PubMed Central

3 November 2017

Yiting Yu

5

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Europe PubMed Central

3 November 2017

Chun Ng

10

1 reference

Europe PubMed Central

3 November 2017

Yongkai Mo

11

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3 November 2017

Wa Shen

12

1 reference

Europe PubMed Central

3 November 2017

Guanghui Kong

14

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Europe PubMed Central

3 November 2017

Ellen Friedman

15

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Europe PubMed Central

3 November 2017

Lei Yan

22

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Europe PubMed Central

3 November 2017

Jonathan M Yingling

23

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Europe PubMed Central

3 November 2017

Michael M Lahn

24

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3 November 2017

Amit Verma

27

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3 November 2017

language of work or name

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publication date

28 December 2010

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Europe PubMed Central

3 November 2017

Cancer Research

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3 November 2017

71

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3 November 2017

3

1 reference

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3 November 2017

955-963

1 reference

Europe PubMed Central

3 November 2017

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

1 reference

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28 May 2018

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

1 reference

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28 May 2018

Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.

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28 May 2018

Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration

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28 May 2018

Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse

1 reference

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28 May 2018

Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.

1 reference

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28 May 2018

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

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28 May 2018

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

1 reference

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28 May 2018

Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in mice

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28 May 2018

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

1 reference

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28 May 2018

Large- and small-molecule inhibitors of transforming growth factor-beta signaling.

1 reference

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28 May 2018

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

1 reference

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28 May 2018

Smad transcription factors

1 reference

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28 May 2018

Cytokine targets in the treatment of myelodysplastic syndromes.

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Functional analysis of human hematopoietic stem cell gene expression using zebrafish

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28 May 2018

Development of TGF-beta signalling inhibitors for cancer therapy

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28 May 2018

A gene atlas of the mouse and human protein-encoding transcriptomes

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28 May 2018

Apoptosis in the myelodysplastic syndromes.

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28 May 2018

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

1 reference

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28 May 2018

1 reference

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28 May 2018

Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment

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International scoring system for evaluating prognosis in myelodysplastic syndromes

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Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions

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Biologic nature of the myelodysplastic syndromes

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Decreased level of transforming growth factor-beta in blood lymphocytes of patients with aplastic anemia

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VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

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Dihydropyrrolopyrazole transforming growth factor-beta type I receptor kinase domain inhibitors: a novel benzimidazole series with selectivity versus transforming growth factor-beta type II receptor kinase and mixed lineage kinase-7.

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Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.

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Gene-expression profiling of CD34+ hematopoietic cells expanded in a collagen I matrix.

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Evidence for reduced B-cell progenitors in early (low-risk) myelodysplastic syndrome.

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Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis

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Prognostic factors and scoring systems in myelodysplastic syndromes.

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Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes

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Involvement of transforming growth factor-beta and thrombopoietin in the pathogenesis of myelodysplastic syndrome with myelofibrosis

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based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphisms in patients with myelodysplastic syndrome

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https://pubmed.ncbi.nlm.nih.gov/21189329

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inferred from PubMed ID database lookup

Gene expression profiling of CD34+cells in patients with the 5q− syndrome

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inferred from PubMed ID database lookup

New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients

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Polymorphisms in TGFbeta and TNFalpha are associated with the myelodysplastic syndrome phenotype

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Measurement of mRNA expression for a variety of cytokines and its receptors in bone marrows of patients with myelodysplastic syndromes

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Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes

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Bone marrow histochemical studies of fibrogenic cytokines and their receptors in myelodysplastic syndrome with myelofibrosis and related disorders

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Biological significance of proliferation, apoptosis, cytokines, and monocyte/macrophage cells in bone marrow biopsies of 145 patients with myelodysplastic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21189329

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based on heuristic

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Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia

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Imbalance between apoptosis and telomerase activity in myelodysplastic syndromes: possible role in ineffective hemopoiesis

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TGF beta signaling in health and disease

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Identifiers

10.1158/0008-5472.CAN-10-2933

1 reference

Europe PubMed Central

3 November 2017

1 reference

Europe PubMed Central

3 November 2017

1 reference

Europe PubMed Central

3 November 2017

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