(Q42599657)

English

Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype

scientific article published on May 2011

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scholarly article

1 reference

Europe PubMed Central

3 November 2017

Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype (English)

1 reference

Europe PubMed Central

3 November 2017

Sriharsha Kantamneni

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

Gareth R Barker

3

1 reference

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15 May 2020

Elizabeth Clea Warburton

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

Emma S. J. Robinson

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

author name string

Laura Ceolin

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

Lydia Hanna

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

Laura Murray

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

James A Monn

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

Stephen M Fitzjohn

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

Graham L Collingridge

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

Zuner A Bortolotto

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

David Lodge

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 May 2011

1 reference

Europe PubMed Central

3 November 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

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15 May 2020

31

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Europe PubMed Central

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15 May 2020

18

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

6721-6731

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological agents acting at subtypes of metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit/hyperactivity disorder (AD/HD).

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neurotransmitter release by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors controlling measures of anxiety and responses to novelty in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of synaptic transmission by mGlu2 and mGlu3 at the perforant path inputs to the dentate gyrus and CA1 revealed in mGlu2 -/- mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral characteristics of rat lines selected for differential hypothermic responses to cholinergic or serotonergic agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group II metabotropic glutamate receptors within the amygdala regulate fear as assessed with potentiated startle in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Born to be anxious: neuroendocrine and genetic correlates of trait anxiety in HAB rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl)pyrid-3-ylmethylamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LY354740, an mGlu2/3 receptor agonist as a novel approach to treat anxiety/stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological and pharmacological characterization of perforant path synapses in CA1: mediation by glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct properties of presynaptic group II and III metabotropic glutamate receptor-mediated inhibition of perforant pathway-CA1 EPSCs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate receptors: identification of a subtype selective mGlu2 receptor agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ascent of mouse: advances in modelling human depression and anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Difference in time course of modulation of synaptic transmission by group II versus group III metabotropic glutamate receptors in region CA1 of the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capabilities of the WinLTP data acquisition program extending beyond basic LTP experimental functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered dimerization of metabotropic glutamate receptor 3 in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and tolerability of an mGlu2/3 agonist in the treatment of generalized anxiety disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039).

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of N-acetylaspartylglutamate (NAAG) at group II mGluRs and NMDAR

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptors: physiology, pharmacology, and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for two physiologically distinct perforant pathways to the fascia dentata

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The perforant path projection to hippocampal area CA1 in the rat hippocampal-entorhinal cortex combined slice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor heterogeneity in rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential involvement of group II and group III mGluRs as autoreceptors at lateral and medial perforant path synapses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxioly

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel orally active group 2 metabotropic glutamate receptor agonist: LY354740.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic and side-effect profile of LY354740: a potent, highly selective, orally active agonist for group II metabotropic glutamate receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of a systemically active group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cells of origin of entorhinal cortical afferents to the hippocampus and fascia dentata of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21543601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0418-11.2011

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632860&resulttype=core&format=json

15 May 2020

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