(Q42601434)

3 November 2017

title

Pharmacological characterization of MP349, a novel 5-HT1A-receptor antagonist with anxiolytic-like activity, in mice and rats (English)

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3 November 2017

4

Ewa Chojnacka-Wójcik

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Krystyna Gołembiowska

series ordinal

3

object named as

Krystyna Gołembiowska

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3 November 2017

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Anna Wesołowska

1

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3 November 2017

Maria H Paluchowska

series ordinal

2

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3 November 2017

Ewa Chojnacka-Wójcik

series ordinal

4

1 reference

3 November 2017

publication date

1 April 2003

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Journal of Pharmacy and Pharmacology

3 November 2017

published in

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3 November 2017

volume

55

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3 November 2017

issue

4

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3 November 2017

page(s)

533-543

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Role of calcium channels in effects of antidepressant drugs on responsiveness to pain.

3 November 2017

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An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat

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Selective activation of 5HT1A receptors induces lower lip retraction in the rat.

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Depletion of brain serotonin differently affects behaviors induced by 5HT1A, 5HT1C, and 5HT2 receptor activation in rats

21 January 2018

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Attenuation of CCK-induced aversion in rats on the elevated x-maze by the selective 5-HT1A receptor antagonists (+) WAY100135 and WAY100635.

21 January 2018

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Anxiolytic-like effect of way-100635 microinfusions into the median (but not dorsal) raphe nucleus in mice exposed to the plus-maze: influence of prior test experience

21 January 2018

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Anxiolytic-like profile of p-MPPI, a novel 5HT1A receptor antagonist, in the murine elevated plus-maze.

21 January 2018

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Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN-190.

21 January 2018

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5-HT1A receptor full and partial agonists and 5-HT2C (but not 5-HT3) receptor antagonists increase rates of punished responding in rats.

21 January 2018

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Effects of 5-HT1A receptor ligands on a safety signal withdrawal procedure of conflict in the rat.

21 January 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

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On the elevated plus-maze the anxiolytic-like effects of the 5-HT(1A) agonist, 8-OH-DPAT, but not the anxiogenic-like effects of the 5-HT(1A) partial agonist, buspirone, are blocked by the 5-HT1A antagonist, WAY 100635.

21 January 2018

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The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other an

21 January 2018

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Modification of the anxiolytic action of 5-HT1A compounds by GABA-benzodiazepine agents in rats.

21 January 2018

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WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

21 January 2018

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Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

21 January 2018

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The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function

21 January 2018

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Predator-elicited flight responses in Swiss-Webster mice: an experimental model of panic attacks

21 January 2018

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Preclinical profile of the mixed 5-HT1A/5-HT2A receptor antagonist S 21,357.

21 January 2018

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The effects of compounds varying in selectivity as 5-HT(1A) receptor antagonists in three rat models of anxiety

21 January 2018

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Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

21 January 2018

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Administration of 8-hydroxy-2-(Di-n-propylamino)tetralin in raphe nuclei dorsalis and medianus reduces serotonin synthesis in the rat brain: differences in potency and regional sensitivity

21 January 2018

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Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated

21 January 2018

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Interaction of GABA and serotonin in the anxiolytic action of diazepam and serotonergic anxiolytics

21 January 2018

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Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys

21 January 2018

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Effects of intra-hippocampal infusion of WAY-100635 on plus-maze behavior in mice. Influence of site of injection and prior test experience

21 January 2018

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Brain monoamine receptors in a chronic unpredictable stress model in rats

21 January 2018

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Active conformation of some arylpiperazine postsynaptic 5-HT(1A) receptor antagonists.

21 January 2018

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Increased anxiety of mice lacking the serotonin1A receptor

21 January 2018

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Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.

21 January 2018

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Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

21 January 2018

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Anxiolytic-like effect of (S)-WAY 100135, a 5-HT1A receptor antagonist, in the murine elevated plus-maze test.

21 January 2018

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Serotonin receptors: subtypes, functional responses and therapeutic relevance.

21 January 2018

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The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-propylamino)tetralin in the rat.

21 January 2018

1 reference

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Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C]WAY-100635

21 January 2018

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Preclinical pharmacology of B-20991, a 5-HT1A receptor agonist with anxiolytic activity

21 January 2018

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Differential effects of ipsapirone on 5-hydroxytryptamine release in the dorsal and median raphe neuronal pathways.

21 January 2018

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Two selective 5-HT1A receptor antagonists, WAY-100 635 and NDL-249, stimulate locomotion in rats acclimatised to their environment and alter their behaviour: a behavioural analysis

21 January 2018

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Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone. IV. Influence of haloperidol (R 1625) and of chlorpromazine on the behaviour of rats in an unfamiliar "open field" situation

21 January 2018

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Structure-activity relationship studies of central nervous system agents. 13. 4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine, a new putative 5-HT1A receptor antagonist, and its analogs

21 January 2018

1 reference

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The role of hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptors in the anticonflict activity of beta-adrenoceptor antagonists

21 January 2018

1 reference

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Somatodendritic 5-HT1A receptors are critically involved in the anxiolytic effects of 8-OH-DPAT

21 January 2018

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A simple and reliable conflict procedure for testing anti-anxiety agents

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1211/0022357021017

1 reference

release_7y6e3sh5bfb4dmte5f4z5q2e5u

3 November 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7y6e3sh5bfb4dmte5f4z5q2e5u

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference