(Q42632645)

English

mRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons

scientific article published on 2 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

mRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons (English)

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

author name string

M Jakobson

1

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

A Lintulahti

2

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

U Arumäe

3

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

publication date

2 February 2012

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

Cell Death and Disease

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

3

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

e269

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Nonsense-mediated decay targets have multiple sequence-related features that can inhibit translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Regulated and quality-control mRNA turnover pathways in eukaryotes

1 reference

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27 May 2018

Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay

1 reference

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27 May 2018

MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

How do miRNAs mediate translational repression?

1 reference

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27 May 2018

Unified translation repression mechanism for microRNAs and upstream AUGs

1 reference

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27 May 2018

Nonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis.

1 reference

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27 May 2018

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

The mammalian nonsense-mediated mRNA decay pathway: to decay or not to decay! Which players make the decision?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?

1 reference

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27 May 2018

Analyzing real-time PCR data by the comparative C(T) method

1 reference

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27 May 2018

The coupling of alternative splicing and nonsense-mediated mRNA decay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Large-scale production of dsRNA and siRNA pools for RNA interference utilizing bacteriophage phi6 RNA-dependent RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

uAUG and uORFs in human and rodent 5'untranslated mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Glucocorticoid receptors in hippocampal neurons that do not engage proteasomes escape from hormone-dependent down-regulation but maintain transactivation activity

1 reference

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27 May 2018

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

1 reference

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27 May 2018

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

1 reference

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27 May 2018

Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Interference of nonsense mutations with eukaryotic messenger RNA stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

27 May 2018

Neurons exclusively express N-Bak, a BH3 domain-only Bak isoform that promotes neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

16 August 2018

Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

16 August 2018

Mutational analysis of N-Bak reveals different structural requirements for antiapoptotic activity in neurons and proapoptotic activity in nonneuronal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

16 August 2018

Exogenous smac induces competence and permits caspase activation in sympathetic neurons.

1 reference

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16 August 2018

Neuron-specific Bcl-2 homology 3 domain-only splice variant of Bak is anti-apoptotic in neurons, but pro-apoptotic in non-neuronal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288346

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BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22297299

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1038/CDDIS.2012.4

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

ResearchGate publication ID

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