(Q42650519)

4 November 2017

title

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix (English)

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4 November 2017

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12

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4 November 2017

Travis C Beddoe

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Phillip I. Bird

object named as

Phillip I Bird

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James C Whisstock

object named as

James C Whisstock

13

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Stephen P Bottomley

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object named as

Stephen P Bottomley

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4 November 2017

Ruby H P Law

1

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4 November 2017

Katya Ruzyla

4

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4 November 2017

Marguerite Buzza

5

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4 November 2017

Tanya A Bashtannyk-Puhalovich

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4 November 2017

Kim Nguyen

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4 November 2017

D Margaret Worrall

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4 November 2017

language of work or name

English

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publication date

10 March 2005

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Journal of Biological Chemistry

4 November 2017

published in

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4 November 2017

volume

280

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4 November 2017

issue

23

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4 November 2017

page(s)

22356-22364

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Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells

4 November 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Multiple functions of maspin in tumor progression and mouse development

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Maspin expression in myoepithelial tumors of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Maspin is an intracellular serpin that partitions into secretory vesicles and is present at the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Maspin sensitizes breast carcinoma cells to induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion. Conversion of ovalbumin to a maspin-like molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Maspin plays an essential role in early embryonic development

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Maspin expression is transactivated by p63 and is critical for the modulation of lung cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

An atlas of serpin conformations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Ovalbumin and angiotensinogen lack serpin S-R conformational change

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Maspin inhibits cell migration in the absence of protease inhibitory activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Solvent content of protein crystals

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Likelihood-enhanced fast rotation functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

Homology modeling, model and software evaluation: three related resources

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412043200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

ALSCRIPT: a tool to format multiple sequence alignments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Crystal structure of ovalbumin as a model for the reactive centre of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Tyrosine phosphorylation of maspin in normal mammary epithelia and breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Different conformational changes within the F-helix occur during serpin folding, polymerization, and proteinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Serpin conformational change in ovalbumin. Enhanced reactive center loop insertion through hinge region mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Recombinant human pigment epithelium-derived factor (PEDF): characterization of PEDF overexpressed and secreted by eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

What do dysfunctional serpins tell us about molecular mobility and disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Crystal structure of S-ovalbumin as a non-loop-inserted thermostabilized serpin form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Roles of electrostatic interaction in proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Probing the unfolding pathway of alpha1-antitrypsin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; evidence for structure in the urea unfolded state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412043200

21 January 2018

Identifiers

DOI

10.1074/JBC.M412043200

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4 November 2017

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