(Q42679550)

4 November 2017

Properties and Mechanism of the Mechanosensitive Ion Channel Inhibitor GsMTx4, a Therapeutic Peptide Derived from Tarantula Venom (English)

1 reference

4 November 2017

0 references

1

1 reference

4 November 2017

Thomas M Suchyna

2

1 reference

PubMed ID

25168134

4 November 2017

Frederick Sachs

series ordinal

3

1 reference

4 November 2017

17 April 2007

1 reference

Current Topics in Membranes

4 November 2017

1 reference

4 November 2017

59

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4 November 2017

81-109

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The breakdown of cell membranes by electrical and mechanical stress

4 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Dynamic signaling between astrocytes and neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Na(+) entry via store-operated channels modulates Ca(2+) signaling in arterial myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

The structures of BtuCD and MscS and their implications for transporter and channel function

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

High-speed pressure clamp

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

A large iris-like expansion of a mechanosensitive channel protein induced by membrane tension

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Cardiac Mechanosensitivity and Stretch-Activated Ion Channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Intermediate filaments and the function of the dystrophin-protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

[24] Mechanosensitive channels of bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Tarantula peptide inhibits atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Sodium influx via a non-selective pathway activated by the removal of extracellular divalent cations: possible role in the calcium paradox

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanotransducing ion channels in astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Dependence of endothelin-1 secretion on Ca2+.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Effect of intracellular Ca2+ concentration on endothelin-1 secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Paradoxical Ca2+ rises induced by low external Ca2+ in rat hippocampal neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanosensitivity of N-type calcium channel currents

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Astrocyte-neurone crosstalk: variants of the same language?

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mediation of cell volume regulation by Ca2+ influx through stretch-activated channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

TRP channels as cellular sensors

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Sensory transduction in the ear.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

New TRP channels in hearing and mechanosensation.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Thrombin is a regulator of astrocytic endothelin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Dipole potentials indicate restructuring of the membrane interface induced by gadolinium and beryllium ions

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Electrophysiological effects of myocardial stretch and mechanical determinants of stretch-activated arrhythmias

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Touch at the molecular level. Mechanosensation

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Molecular basis of mechanosensory transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

C-terminal amidation of neuropeptides. Gly-Lys-Arg extension an efficient precursor of C-terminal amide

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Stretch-activation and stretch-inactivation of Shaker-IR, a voltage-gated K+ channel

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Molecular basis of mechanotransduction in living cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Amiloride: a molecular probe for mechanosensitive channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Activation of endothelin receptors by sarafotoxin regulates Ca2+ homeostasis in cerebellar astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Desensitization of mechano-gated K2P channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Stretch-activated ion channels in the heart

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Putting ion channels to work: mechanoelectrical transduction, adaptation, and amplification by hair cells

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Genistein Can Modulate Channel Function by a Phosphorylation-Independent Mechanism: Importance of Hydrophobic Mismatch and Bilayer Mechanics

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Endothelin-1 regulates cytosolic and nuclear Ca2+ in human endocardial endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Ca2+ influx through mechanosensitive channels inhibits neurite outgrowth in opposition to other influx pathways and release from intracellular stores

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

X-ray structure of a voltage-dependent K+ channel

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

The principle of gating charge movement in a voltage-dependent K+ channel

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Pharmacological strategies for muscular dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Thrombin-stimulated phosphorylation of myosin light chain and its possible involvement in endothelin-1 secretion from porcine aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Effects of acute ventricular volume manipulation on in situ cardiomyocyte cell membrane configuration.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Membrane tension accelerates rate-limiting voltage-dependent activation and slow inactivation steps in a Shaker channel

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Solution structure and functional characterization of SGTx1, a modifier of Kv2.1 channel gating

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Therapeutic potential of venom peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Are several G proteins involved in the different effects of endothelin-1 in mouse striatal astrocytes?

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

TRPC1 forms the stretch-activated cation channel in vertebrate cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Astrocytes are target cells for endothelins and sarafotoxin.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanosensitive channels in prokaryotes.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Evolutionary origins of mechanosensitive ion channels.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Molecular and cellular mechanism of endothelin regulation. Implications for vascular function

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Neuronal plasma membrane dynamics evoked by osmomechanical perturbations

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Drosophila mutant with a transducer defect

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Rescue of the Drosophila phototransduction mutation trp by germline transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Role of Ca2+ and protein kinase C in shear stress-induced actin depolymerization and endothelin 1 gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Usefulness and limitations of linear approximations to the understanding of Ca++ signals

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Dynamic properties of stretch-activated K+ channels in adult rat atrial myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Cellular basis of ventricular arrhythmias and abnormal automaticity in heart failure.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Gadolinium uncouples mechanical detection and osmoreceptor potential in supraoptic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanosensation and endothelin in astrocytes--hypothetical roles in CNS pathophysiology

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Stretch-induced endothelin-1 production by astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Solution structure of peptide toxins that block mechanosensitive ion channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Lipid and mechano-gated 2P domain K(+) channels.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Pharmacological control of cellular calcium handling in dystrophic skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Retaining your identity under stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanosensitive ion channels in nonspecialized cells

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Biological membranes as bilayer couples. III. Compensatory shape changes induced in membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Voltage-dependent ion channels in glial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

A common mechanism underlies stretch activation and receptor activation of TRPC6 channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Dynamic regulation of mechanosensitive channels: capacitance used to monitor patch tension in real time.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanosensitive channels: what can we learn from ?simple? model systems?

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

A large-conductance mechanosensitive channel in E. coli encoded by mscL alone

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Energetic and spatial parameters for gating of the bacterial large conductance mechanosensitive channel, MscL

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Free calcium rise and mitogenesis in glial cells caused by endothelin.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Characterization of a functionally expressed stretch-activated BKca channel cloned from chick ventricular myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Role of the cytoskeleton in Ca2+ release from the intracellular Ca store of rat peritoneal mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

FMRFamide and membrane stretch as activators of the Aplysia S-channel

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Effect of mechanogated membrane ion channel blockers on experimental traumatic brain oedema.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Responses of neurons to extreme osmomechanical stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Molecular surface of tarantula toxins interacting with voltage sensors in K(v) channels

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Protein folding in membranes: determining energetics of peptide-bilayer interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Analytic models for mechanotransduction: gating a mechanosensitive channel

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Gadolinium reduces short-term stretch-induced muscle damage in isolated mdx mouse muscle fibres

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Effects of stretch-activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Calcium oscillations encoding neuron-to-astrocyte communication

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation.

1 reference

https://api.crossref.org/works/10.1016%2FS1063-5823%2806%2959004-0

7 January 2021

10.1016/S1063-5823(06)59004-0

Identifiers

DOI

1 reference

4 November 2017

1 reference

PubMed ID

25168134