(Q42686364)

4 November 2017

Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis (English)

1 reference

4 November 2017

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1 reference

1 reference

Adam E Snook

8

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Scott A. Waldman

object named as

Scott A Waldman

13

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author name string

Jieru E Lin

1

1 reference

4 November 2017

Francheska Colon-Gonzalez

2

1 reference

4 November 2017

Erik Blomain

3

1 reference

4 November 2017

Gilbert W Kim

4

1 reference

4 November 2017

Amanda Aing

5

1 reference

4 November 2017

Brian Stoecker

6

1 reference

4 November 2017

Justin Rock

7

1 reference

4 November 2017

Tingting Zhan

9

1 reference

4 November 2017

Terry M Hyslop

10

1 reference

4 November 2017

Michal Tomczak

11

1 reference

4 November 2017

Richard S Blumberg

12

1 reference

4 November 2017

language of work or name

English

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publication date

1 January 2016

1 reference

4 November 2017

1 reference

4 November 2017

76

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4 November 2017

2

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4 November 2017

339-346

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Global burden of cancer attributable to high body-mass index in 2012: a population-based study

4 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Paneth cells as a site of origin for intestinal inflammation.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Sarco(endo)plasmic reticulum Ca 2+ -ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-alpha mice.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

The paracrine hormone hypothesis of colorectal cancer.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Obesity-induced inflammatory changes in adipose tissue.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Bacterial enterotoxins are associated with resistance to colon cancer.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Leptin and the regulation of body weight in mammals

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Gene expression profiles in normal and cancer cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Two randomized trials of linaclotide for chronic constipation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4717834

Expression of guanylin is downregulated in mouse and human intestinal adenomas

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26773096

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26773096

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-15-1467-T

1 reference

4 November 2017

1 reference

4 November 2017

PubMed publication ID

26773096

1 reference