(Q42702942)

English

A Phase I Study of CUDC-101, a Multitarget Inhibitor of HDACs, EGFR, and HER2, in Combination with Chemoradiation in Patients with Head and Neck Squamous Cell Carcinoma

scientific article published on 8 January 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

A Phase I Study of CUDC-101, a Multitarget Inhibitor of HDACs, EGFR, and HER2, in Combination with Chemoradiation in Patients with Head and Neck Squamous Cell Carcinoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

chemoradiotherapy

0 references

Barbara Burtness

12

object named as

Barbara Burtness

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

author name string

Thomas J Galloway

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Lori J Wirth

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Alexander D Colevas

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Jill Gilbert

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Julie E Bauman

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Nabil F Saba

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

David Raben

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Ranee Mehra

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Anna W Ma

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Ruzanna Atoyan

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Jing Wang

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Antonio Jimeno

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

8 January 2015

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

Clinical Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

1566-1573

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

Targeting HER2 in other tumor types

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancing the antitumor activity of ErbB blockade with histone deacetylase (HDAC) inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of cellular radiation responses by histone deacetylase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor biology in head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of gamma-H2AX foci

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic impact of HER-2/neu expression on squamous head and neck carcinomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective risk-adjusted [18F]Fluorodeoxyglucose positron emission tomography and computed tomography assessment of radiation response in head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CUDC-101, a multitargeted inhibitor of histone deacetylase, epidermal growth factor receptor, and human epidermal growth factor receptor 2, exerts potent anticancer activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human papillomavirus and survival of patients with oropharyngeal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase-1 and -2 expression in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mutational landscape of head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of lapatinib monotherapy: results of a randomised phase II study in therapy-naive patients with locally advanced squamous cell carcinoma of the head and neck

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II study of lapatinib in recurrent/metastatic squamous cell carcinoma of the head and neck.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear epidermal growth factor receptor and p16 expression in head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomised Phase II study of oral lapatinib combined with chemoradiotherapy in patients with advanced squamous cell carcinoma of the head and neck: rationale for future randomised trials in human papilloma virus-negative disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel targets in HPV-negative head and neck cancer: overcoming resistance to EGFR inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer statistics, 2014

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improving the efficacy of chemoradiation with targeted agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel insight into mutational landscape of head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vorinostat as a radiosensitizer for brain metastasis: a phase I clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I first-in-human study of CUDC-101, a multitargeted inhibitor of HDACs, EGFR, and HER2 in patients with advanced solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER2 as a therapeutic target in head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25573383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-14-2820

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6607903&resulttype=core&format=json

15 May 2020

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