(Q42704294)

5 November 2017

Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor (English)

1 reference

5 November 2017

5

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5 November 2017

Y Baqi

4

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author name string

K Hoffmann

1

1 reference

5 November 2017

D A Lutz

2

1 reference

5 November 2017

J Straßburger

3

1 reference

5 November 2017

I von Kügelgen

6

1 reference

5 November 2017

29 September 2014

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Journal of Thrombosis and Haemostasis

5 November 2017

1 reference

5 November 2017

12

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5 November 2017

11

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5 November 2017

1898-1905

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Identification of the platelet ADP receptor targeted by antithrombotic drugs

5 November 2017

1 reference

Central role of the P2Y12 receptor in platelet activation

21 January 2018

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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

21 January 2018

1 reference

Molecular pharmacology, physiology, and structure of the P2Y receptors

21 January 2018

1 reference

The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts

21 January 2018

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Interaction of the active metabolite of prasugrel, R-138727, with cysteine 97 and cysteine 175 of the human P2Y12 receptor

21 January 2018

1 reference

Reduction in first and recurrent cardiovascular events with ticagrelor compared with clopidogrel in the PLATO Study.

21 January 2018

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Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation.

21 January 2018

1 reference

Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding

21 January 2018

1 reference

Identification and characterization of a novel P2Y 12 variant in a patient diagnosed with type 1 von Willebrand disease in the European MCMDM-1VWD study

21 January 2018

1 reference

Involvement of basic amino acid residues in transmembrane regions 6 and 7 in agonist and antagonist recognition of the human platelet P2Y(12)-receptor

21 January 2018

1 reference

Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor

21 January 2018

1 reference

Mutational analysis of residues important for ligand interaction with the human P2Y(12) receptor

21 January 2018

1 reference

Using ortholog sequence data to predict the functional relevance of mutations in G-protein-coupled receptors

21 January 2018

1 reference

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

21 January 2018

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Agonist-bound structure of the human P2Y12 receptor

21 January 2018

1 reference

High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

21 January 2018

1 reference

High-resolution crystal structure of human protease-activated receptor 1

21 January 2018

1 reference

The platelet P2Y(12) receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [(3)H]PSB-0413.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/JTH.12719

1 reference

5 November 2017

1 reference