(Q42706171)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

title

Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

1 reference

Crithidia fasciculata

object named as

Crithidia fasciculata

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

author name string

J A Ponasik

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

C Strickland

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

C Faerman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

S Savvides

4

1 reference

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19 October 2019

B Ganem

6

1 reference

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19 October 2019

language of work or name

English

0 references

publication date

1 October 1995

1 reference

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19 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

volume

311 ( Pt 2)

1 reference

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19 October 2019

page(s)

371-375

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

Substrate interactions between trypanothione reductase and N1-glutathionylspermidine disulphide at 0.28-nm resolution

19 October 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

The structure of Trypanosoma cruzi trypanothione reductase in the oxidized and NADPH reduced state

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Refined structure of glutathione reductase at 1.54 A resolution

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

"Subversive" substrates for the enzyme trypanothione disulfide reductase: alternative approach to chemotherapy of Chagas disease

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Trypanothione is the primary target for arsenical drugs against African trypanosomes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 A resolution

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Molecular studies on trypanothione reductase, a target for antiparasitic drugs

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-A resolution

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Active site of trypanothione reductase. A target for rational drug design.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Metabolism and functions of trypanothione in the Kinetoplastida

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

6 Statistical analysis of enzyme kinetic data

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatids.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Structure of trypanothione reductase from Crithidia fasciculata at 2.6 A resolution; enzyme-NADP interactions at 2.8 A resolution

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Oxidative stress as a defense mechanism against parasitic infections

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Role of the charged groups of glutathione disulfide in the catalysis of glutathione reductase: crystallographic and kinetic studies with synthetic analogues

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136010

Overexpression of Crithidia fasciculata trypanothione reductase and crystallization using a novel geometry

16 August 2018

1 reference

12 December 2020

Chinifur, a selective inhibitor and "subversive substrate" for Trypanosoma congolense trypanothione reductase

1 reference

12 December 2020

Polyamines as physiological substrates for transglutaminases

1 reference

12 December 2020

A crystallographic study of the glutathione binding site of glutathione reductase at 0.3-nm resolution

1 reference

12 December 2020

The survival of Plasmodium Under oxidant stress

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ3110371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7487870%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

PubMed publication ID

7487870

1 reference