(Q42713397)

5 November 2017

title

Long-term stability of primary rat hepatocytes in micropatterned cocultures (English)

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5 November 2017

12

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5 November 2017

Melvin E Andersen

10

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author name string

Okechukwu Ukairo

1

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5 November 2017

Chitra Kanchagar

2

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Amanda Moore

3

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Julianne Shi

4

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Jeannemarie Gaffney

5

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Simon Aoyama

6

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Kelly Rose

7

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Stacy Krzyzewski

8

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Jack McGeehan

9

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Salman R Khetani

11

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5 November 2017

publication date

11 January 2013

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Journal of Biochemical and Molecular Toxicology

5 November 2017

published in

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5 November 2017

volume

27

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5 November 2017

issue

3

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5 November 2017

page(s)

204-212

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New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures

5 November 2017

cites work

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A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction

21 January 2018

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Liver cell models in in vitro toxicology

21 January 2018

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Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

21 January 2018

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Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties

21 January 2018

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Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.

21 January 2018

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Microscale culture of human liver cells for drug development.

21 January 2018

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Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites

21 January 2018

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Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes.

21 January 2018

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Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats from dietary exposure to potassium perfluorooctanesulfonate results from increased expression of xenosensor nuclear receptors PPARα and CAR/PXR.

21 January 2018

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Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human

21 January 2018

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Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells

21 January 2018

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Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes

21 January 2018

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Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.

21 January 2018

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Bupropion hydroxylation as a selective marker of rat CYP2B1 catalytic activity.

21 January 2018

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Membrane transporters in drug development

21 January 2018

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Actin filament alterations in rat hepatocytes induced in vivo and in vitro by microcystin-LR, a hepatotoxin from the blue-green alga, Microcystis aeruginosa.

21 January 2018

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Quantitative expression profile of hepatobiliary transporters in sandwich cultured rat and human hepatocytes

21 January 2018

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FDA-approved drug labeling for the study of drug-induced liver injury

21 January 2018

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Idiosyncratic drug hepatotoxicity

21 January 2018

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In vitro evaluation of potential hepatotoxicity induced by drugs.

21 January 2018

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Cutting the cost of drug development?

21 January 2018

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T-cadherin modulates hepatocyte functions in vitro

21 January 2018

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Exploring interactions between rat hepatocytes and nonparenchymal cells using gene expression profiling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JBT.21469

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5 November 2017

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