(Q42716028)

5 November 2017

title

Toxicity profile of small-molecule IAP antagonist GDC-0152 is linked to TNF-α pharmacology (English)

1 reference

5 November 2017

0 references

1 reference

Rebecca I Erickson

1

1 reference

5 November 2017

Jacqueline Tarrant

2

1 reference

5 November 2017

Gary Cain

3

1 reference

5 November 2017

Sock-Cheng Lewin-Koh

4

1 reference

5 November 2017

Noel Dybdal

5

1 reference

5 November 2017

Harvey Wong

6

1 reference

5 November 2017

Elizabeth Blackwood

7

1 reference

5 November 2017

Kristina West

8

1 reference

5 November 2017

Ronald Steigerwalt

9

1 reference

5 November 2017

Michael Mamounas

10

1 reference

5 November 2017

John A Flygare

11

1 reference

5 November 2017

Kenjie Amemiya

12

1 reference

5 November 2017

Donna Dambach

13

1 reference

5 November 2017

Wayne J Fairbrother

14

1 reference

5 November 2017

Dolores Diaz

15

1 reference

5 November 2017

publication date

5 September 2012

1 reference

5 November 2017

published in

Toxicological Sciences

1 reference

5 November 2017

volume

131

1 reference

5 November 2017

issue

1

1 reference

5 November 2017

page(s)

247-258

1 reference

Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma.

5 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Budd-Chiari syndrome: etiology, pathogenesis and diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Acute phase proteins in dogs and cats: current knowledge and future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Corticosteroid-Induced Lymphopenia, Immunosuppression, and Body Defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Small-molecule pan-IAP antagonists: a patent review

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

High serum levels of TNF-α after its administration for isolation perfusion of the limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Kupffer cell-mediated cytotoxicity induced by lipopolysaccharide0111:B4 is greater in dogs than in rats and monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Serum C-reactive protein (CRP) levels in cancer patients are linked with tumor burden and are reduced by anti-hypertensive medication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Circulating cytokines as mediators of fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Systemic use of tumor necrosis factor alpha as an anticancer agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Blood cytokines as biomarkers of in vivo toxicity in preclinical safety assessment: considerations for their use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Shock and tissue injury induced by recombinant human cachectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Tumor necrosis factor: an apoptosis JuNKie?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

A comparative analysis of acute-phase proteins as inflammatory biomarkers in preclinical toxicology studies: implications for preclinical to clinical translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFS265

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFS265

1 reference

5 November 2017

1 reference