(Q42717337)

5 November 2017

Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome (English)

1 reference

human embryonic stem cell

5 November 2017

1 reference

11

1 reference

5 November 2017

Bastian Zimmer

3

0 references

Jürgen Hescheler

9

object named as

Jürgen Hescheler

1 reference

5 November 2017

8

Agapios Sachinidis

1 reference

5 November 2017

7

Smita Jagtap

1 reference

5 November 2017

10

Tanja Waldmann

1 reference

5 November 2017

1

Nina V Balmer

1 reference

5 November 2017

Matthias K Weng

2

1 reference

5 November 2017

Violeta N Ivanova

4

1 reference

5 November 2017

Stuart M Chambers

5

1 reference

5 November 2017

Elena Nikolaeva

6

1 reference

5 November 2017

20 June 2012

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5 November 2017

Human Molecular Genetics

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5 November 2017

21

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5 November 2017

18

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5 November 2017

4104-4114

1 reference

Modelling long QT syndrome with iPS cells: be still, my beating heart ...

5 November 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Modelling schizophrenia using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

A human stem cell model of early Alzheimer's disease pathology in Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Dynamic DNA methylation programs persistent adverse effects of early-life stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Early life experience alters response of adult neurogenesis to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

The fetal valproate syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Valproic acid monotherapy in pregnancy and major congenital malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Experimental studies on cervical and lumbar ribs in mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Spina bifida aperta induced by valproic acid and by all-trans-retinoic acid in the mouse: distinct differences in morphology and periods of sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Malformations, withdrawal manifestations, and hypoglycaemia after exposure to valproate in utero

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

The critical period of valproate exposure to induce autistic symptoms in Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

In-utero exposure to valproate and neural tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

PAX-6 in development and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

An in ovo chicken model to study the systemic and localized teratogenic effects of valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Action of valproic acid on Xenopus laevis development: teratogenic effects on eyes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Valproic acid increases formation of reactive oxygen species and induces apoptosis in postimplantation embryos: a role for oxidative stress in valproic acid-induced neural tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Identification of small molecules from human embryonic stem cells using metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Mode of action: inhibition of histone deacetylase, altering WNT-dependent gene expression, and regulation of beta-catenin--developmental effects of valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Epigenetic regulation of nervous system development by DNA methylation and histone deacetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Valproic acid teratogenicity: a toxicogenomics approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Histone deacetylase inhibitors: understanding a new wave of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Active genes are tri-methylated at K4 of histone H3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Chromatin modifications and their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Mechanisms of transcriptional repression by histone lysine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Molecular mechanisms controlling brain development: an overview of neuroepithelial secondary organizers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Fibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Integrating genetic and toxicogenomic information for determining underlying susceptibility to developmental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Candidate gene analysis in human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Arsenic- and cadmium-induced toxicogenomic response in mouse embryos undergoing neurulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

The genetic basis of mammalian neurulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Valproic acid toxicity: overview and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Valproic acid-induced deregulation in vitro of genes associated in vivo with neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Control of EGF receptor signaling by clathrin-mediated endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Epigenetic modifications in valproic acid-induced teratogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

g:Profiler--a web server for functional interpretation of gene lists (2011 update).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS239

Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo

21 January 2018

1 reference

27 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1096/FJ.04-3425FJE

Identifiers

DOI

10.1093/HMG/DDS239

1 reference

5 November 2017

1 reference