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AMPK couples p73 with p53 in cell fate decision.
scientific article published on 30 May 2014
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Europe PubMed Central
PMCID
4131177
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24874608%20AND%20SRC:MED&resulttype=core&format=json
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19 March 2020
title
AMPK couples p73 with p53 in cell fate decision
(English)
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Europe PubMed Central
PMCID
4131177
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24874608%20AND%20SRC:MED&resulttype=core&format=json
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19 March 2020
author
Nina Reuven
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4
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4131177
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19 March 2020
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Y Adamovich
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1
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4131177
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19 March 2020
J Adler
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2
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4131177
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19 March 2020
V Meltser
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3
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19 March 2020
Y Shaul
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5
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19 March 2020
publication date
30 May 2014
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19 March 2020
published in
Cell Death & Differentiation
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4131177
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19 March 2020
volume
21
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19 March 2020
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9
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4131177
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19 March 2020
page(s)
1451-1459
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19 March 2020
exact match
https://scigraph.springernature.com/pub.10.1038/cdd.2014.60
0 references
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LKB1/AMPK/mTOR signaling pathway in hematological malignancies: from metabolism to cancer cell biology.
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p73 as a pharmaceutical target for cancer therapy
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The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway
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AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol
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The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting.
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The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
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27 May 2018
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.
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Kinase activity-independent suppression of p73alpha by AMP-activated kinase alpha (AMPKalpha).
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AMP-activated protein kinase and human cancer: cancer metabolism revisited
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AMPK phosphorylation of raptor mediates a metabolic checkpoint
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Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
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ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin
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27 May 2018
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
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Regulation of p73-mediated apoptosis by c-Jun N-terminal kinase
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27 May 2018
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.
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27 May 2018
AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancer
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p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.
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The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.
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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
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A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73
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27 May 2018
The ubiquitin-protein ligase Itch regulates p73 stability
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27 May 2018
p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2.
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E1A activates transcription of p73 and Noxa to induce apoptosis
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Ubiquitin-dependent degradation of p73 is inhibited by PML.
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p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation
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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
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Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs
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Nuclear import and export signals in control of the p53-related protein p73.
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Regulation of p73 by c-Abl through the p38 MAP kinase pathway.
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AMP-activated protein kinase: the energy charge hypothesis revisited
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Role of AMP-activated protein kinase in mechanism of metformin action
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Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line
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27 May 2018
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
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27 May 2018
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain
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27 May 2018
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
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27 May 2018
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
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27 May 2018
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
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27 May 2018
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
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27 May 2018
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
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27 May 2018
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
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27 May 2018
Interaction between ATM protein and c-Abl in response to DNA damage
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27 May 2018
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
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27 May 2018
Regulation of p53 stability by Mdm2
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27 May 2018
Mdm2 promotes the rapid degradation of p53
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27 May 2018
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
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27 May 2018
Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress
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16 August 2018
c-Abl tyrosine kinase selectively regulates p73 nuclear matrix association.
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16 August 2018
Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate.
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16 August 2018
Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73
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21 January 2018
p73β Is Regulated by Protein Kinase Cδ Catalytic Fragment Generated in the Apoptotic Response to DNA Damage
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21 January 2018
Identifiers
DOI
10.1038/CDD.2014.60
1 reference
stated in
Europe PubMed Central
PMCID
4131177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24874608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 March 2020
Dimensions Publication ID
1031066003
0 references
PMCID
4131177
1 reference
stated in
Europe PubMed Central
PMCID
4131177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24874608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 March 2020
PubMed ID
24874608
1 reference
stated in
Europe PubMed Central
PMCID
4131177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24874608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 March 2020
ResearchGate publication ID
262787398
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