(Q42803804)

7 November 2017

title

Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts (English)

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7 November 2017

4

Kahn CR

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7 November 2017

Winnay JN

1

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7 November 2017

Brüning JC

series ordinal

2

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7 November 2017

Burks DJ

series ordinal

3

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7 November 2017

language of work or name

English

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publication date

1 April 2000

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Journal of Biological Chemistry

7 November 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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7 November 2017

volume

275

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7 November 2017

issue

14

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7 November 2017

page(s)

10545-10550

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

7 November 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Role of IRS-2 in insulin and cytokine signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Detection of a 60 kDa tyrosine-phosphorylated protein in insulin-stimulated hepatoma cells that associates with the SH2 domain of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Characterization of insulin receptor substrate 4 in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Involvement of Src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Shc isoform-specific tyrosine phosphorylation by the insulin and epidermal growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Heterologous pleckstrin homology domains do not couple IRS-1 to the insulin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Crystal structure of the tyrosine kinase domain of the human insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10545

21 January 2018

Identifiers

DOI

10.1074/JBC.275.14.10545

1 reference

7 November 2017

1 reference