(Q42809646)

7 November 2017

The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia (English)

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7 November 2017

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1 reference

Isabel Moreno-Miralles

1

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7 November 2017

Ling Pan

2

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7 November 2017

Jennifer Keates-Baleeiro

3

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7 November 2017

Kristie Durst-Goodwin

4

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7 November 2017

Chunying Yang

5

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7 November 2017

Hyung-Gyoon Kim

6

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7 November 2017

Mary Ann Thompson

7

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7 November 2017

Christopher A Klug

8

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7 November 2017

John L Cleveland

9

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7 November 2017

Scott W Hiebert

10

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7 November 2017

language of work or name

English

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publication date

30 September 2005

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Journal of Biological Chemistry

7 November 2017

7

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based on heuristic

inferred from page(s)

published in

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7 November 2017

280

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7 November 2017

48

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7 November 2017

40097-40103

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

7 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

The PEBP2beta/CBF beta-SMMHC chimeric protein is localized both in the cell membrane and nuclear subfractions of leukemic cells carrying chromosomal inversion 16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506855200

21 January 2018

Identifiers

DOI

10.1074/JBC.M506855200

1 reference

7 November 2017

1 reference