(Q42818861)

English

Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib

scientific article published on 25 May 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

author name string

Shingen Nakamura

1

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Hirokazu Miki

2

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Shinsuke Kido

3

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Ayako Nakano

4

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Masahiro Hiasa

5

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Asuka Oda

6

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Hiroe Amou

7

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Keiichiro Watanabe

8

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Takeshi Harada

9

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Shiro Fujii

10

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Kyoko Takeuchi

11

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Kumiko Kagawa

12

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Shuji Ozaki

13

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Toshio Matsumoto

14

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Masahiro Abe

15

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

publication date

25 May 2013

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Europe PubMed Central

PubMed publication ID

7 November 2017

International Journal of Hematology

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

98

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7 November 2017

1

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7 November 2017

66-73

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Targeting the interplay between myeloma cells and the bone marrow microenvironment in myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Therapy with bortezomib plus dexamethasone induces osteoblast activation in responsive patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patients

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Bortezomib induces osteoblast differentiation via Wnt-independent activation of beta-catenin/TCF signaling

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling.

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

From endoplasmic-reticulum stress to the inflammatory response

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Transcription factors controlling osteoblastogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

CCAAT/enhancer-binding protein beta promotes osteoblast differentiation by enhancing Runx2 activity with ATF4.

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Stimulation by 1,25-dihydroxyvitamin D3 of in vitro mineralization induced by osteoblast-like MC3T3-E1 cells

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2.

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

GM-CSF and IL-4 induce dendritic cell differentiation and disrupt osteoclastogenesis through M-CSF receptor shedding by up-regulation of TNF-alpha converting enzyme (TACE).

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Prospective comparison of subcutaneous versus intravenous administration of bortezomib in patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

In vitro and in vivo selective antitumor activity of a novel orally bioavailable proteasome inhibitor MLN9708 against multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Antitumor activity of the investigational proteasome inhibitor MLN9708 in mouse models of B-cell and plasma cell malignancies

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma.

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Osteoblastogenesis and tumor growth in myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS12185-013-1367-Z

21 January 2018

Sotatercept, a soluble activin receptor type 2A IgG-Fc fusion protein for the treatment of anemia and bone loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/23708974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23708974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23708974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23708974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12185-013-1367-Z

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

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