(Q42827947)

8 November 2017

title

Smad2 phosphorylation by type I receptor: contribution of arginine 462 and cysteine 463 In the C terminus of Smad2 for specificity (English)

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8 November 2017

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Ihor Yakymovych

1

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8 November 2017

Carl-Henrik Heldin

series ordinal

2

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8 November 2017

Serhiy Souchelnytskyi

series ordinal

3

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8 November 2017

language of work or name

English

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publication date

21 June 2004

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Journal of Biological Chemistry

8 November 2017

published in

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8 November 2017

volume

279

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8 November 2017

issue

34

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8 November 2017

page(s)

35781-35787

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

8 November 2017

cites work

1 reference

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

21 January 2018

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TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

21 January 2018

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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

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A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity

21 January 2018

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Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors

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Structural basis of Smad2 recognition by the Smad anchor for receptor activation

21 January 2018

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Structural basis of Smad1 activation by receptor kinase phosphorylation

21 January 2018

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The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization

21 January 2018

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A structural basis for mutational inactivation of the tumour suppressor Smad4

21 January 2018

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Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations

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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

21 January 2018

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Inhibition of transforming growth factor-beta signaling by low molecular weight compounds interfering with ATP- or substrate-binding sites of the TGF beta type I receptor kinase

21 January 2018

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Regulation of Smad signaling by protein kinase C

21 January 2018

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Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry

21 January 2018

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 January 2018

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High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

21 January 2018

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Smad4 and FAST-1 in the assembly of activin-responsive factor

21 January 2018

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The specificity of the transforming growth factor beta receptor kinases determined by a spatially addressable peptide library

21 January 2018

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Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

21 January 2018

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

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Crystal Structure of a Phosphorylated Smad2

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M404377200

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8 November 2017

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