(Q42831893)

8 November 2017

title

Increased GIP signaling induces adipose inflammation via a HIF-1α-dependent pathway and impairs insulin sensitivity in mice (English)

1 reference

8 November 2017

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Shu Chen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Fumiaki Okahara

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Noriko Osaki

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

publication date

23 December 2014

1 reference

American Journal of Physiology - Endocrinology and Metabolism

8 November 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

E414-25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

12 June 2020

cites work

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Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss

21 January 2018

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Glucose-dependent insulin release from genetically engineered K cells

21 January 2018

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The biology of incretin hormones

21 January 2018

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Abnormalities of GIP in spontaneous syndromes of obesity and diabetes in mice

21 January 2018

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High-fat feeding stimulates endocrine, glucose-dependent insulinotropic polypeptide (GIP)-expressing cell hyperplasia in the duodenum of Wistar rats.

21 January 2018

1 reference

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Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

21 January 2018

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Inflammation and metabolic disorders

21 January 2018

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

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Diet and risk of Type II diabetes: the role of types of fat and carbohydrate

21 January 2018

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Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice

21 January 2018

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Involvement of mitochondrial- and Fas-mediated dual mechanism in CoCl2-induced apoptosis of rat PC12 cells

21 January 2018

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Mechanisms linking obesity to insulin resistance and type 2 diabetes

21 January 2018

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Deletion of hypoxia-inducible factor-1α in adipocytes enhances glucagon-like peptide-1 secretion and reduces adipose tissue inflammation

21 January 2018

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Activation of lipoprotein lipase by glucose-dependent insulinotropic polypeptide in adipocytes. A role for a protein kinase B, LKB1, and AMP-activated protein kinase cascade

21 January 2018

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Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation

21 January 2018

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Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity

21 January 2018

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Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes

21 January 2018

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Inhibition of gastric inhibitory polypeptide signaling prevents obesity

21 January 2018

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Gastric inhibitory peptide controls adipose insulin sensitivity via activation of cAMP-response element-binding protein and p110β isoform of phosphatidylinositol 3-kinase

21 January 2018

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Nitric oxide, oxygen, and superoxide formation and consumption in macrophage cultures

21 January 2018

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Glucose-dependent insulinotropic peptide impairs insulin signaling via inducing adipocyte inflammation in glucose-dependent insulinotropic peptide receptor-overexpressing adipocytes

21 January 2018

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Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors

21 January 2018

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Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

21 January 2018

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Hypoxia decreases insulin signaling pathways in adipocytes

21 January 2018

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Adipose tissue: from lipid storage compartment to endocrine organ

21 January 2018

1 reference

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GIP and GLP-1, the two incretin hormones: Similarities and differences

21 January 2018

1 reference

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HIF-1: mediator of physiological and pathophysiological responses to hypoxia

21 January 2018

1 reference

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Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation.

21 January 2018

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A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

21 January 2018

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Diet-induced type II diabetes in C57BL/6J mice

21 January 2018

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Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes.

21 January 2018

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Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

21 January 2018

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21 January 2018

Biology of HIF-1alpha

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00418.2014

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

21 January 2018

1 reference

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

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Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice

21 January 2018

1 reference

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10.1152/AJPENDO.00418.2014

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25537494%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference