(Q42831990)

English

SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes

scientific article published on 26 January 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

Tsutomu Wada

2

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author name string

Toshiyasu Sasaoka

1

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Kazuhito Fukui

3

1 reference

Europe PubMed Central

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8 November 2017

Shihou Murakami

4

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Hajime Ishihara

5

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Ryo Suzuki

6

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Kazuyuki Tobe

7

1 reference

Europe PubMed Central

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8 November 2017

Takashi Kadowaki

8

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Europe PubMed Central

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8 November 2017

Masashi Kobayashi

9

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8 November 2017

language of work or name

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publication date

26 January 2004

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Europe PubMed Central

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8 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

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8 November 2017

279

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Europe PubMed Central

PubMed publication ID

8 November 2017

15

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Europe PubMed Central

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8 November 2017

14835-14843

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Europe PubMed Central

PubMed publication ID

8 November 2017

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

The role of phosphoinositide 3-kinase lipid products in cell function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Identification of a Second SH2-Domain-Containing Protein Closely Related to the Phosphatidylinositol Polyphosphate 5-Phosphatase SHIP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

The lipid phosphatase SHIP2 controls insulin sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Insulin Increases the Association of Akt-2 with Glut4-containing Vesicles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Insulin Regulation of Membrane-associated Insulin Receptor Substrate 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Membrane localization of Src homology 2-containing inositol 5'-phosphatase 2 via Shc association is required for the negative regulation of insulin signaling in Rat1 fibroblasts overexpressing insulin receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Insights into insulin resistance and type 2 diabetes from knockout mouse models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Growth factors and insulin stimulate tyrosine phosphorylation of the 51C/SHIP2 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311534200

21 January 2018

Identifiers

10.1074/JBC.M311534200

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

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