(Q42840910)

English

Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.

scientific article published on November 2010

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15 January 2020

Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21038414%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Pietro Invernizzi

5

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15 January 2020

9

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15 January 2020

Sacha Ferdinandusse

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Sacha Ferdinandusse

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15 January 2020

Michael Trauner

10

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Michael Trauner

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15 January 2020

Andrea Fuchsbichler

8

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Andrea Fuchsbichler

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15 January 2020

11

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Alan F Hofmann

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15 January 2020

12

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Ulrich Beuers

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15 January 2020

3

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Ralf Wimmer

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15 January 2020

Christian Jakob Friedrich Ruest

4

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Christian Rust

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15 January 2020

1

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Gerald U Denk

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15 January 2020

author name string

Silvia Maitz

2

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15 January 2020

Wim Kulik

7

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15 January 2020

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publication date

1 November 2010

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15 January 2020

1 reference

Europe PubMed Central

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15 January 2020

52

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15 January 2020

5

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15 January 2020

1758-1768

1 reference

Europe PubMed Central

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15 January 2020

Hepatic injury induced by bile salts: correlation between biochemical and morphological events

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Excellent long-term survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic Acid

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved prognosis of patients with primary biliary cirrhosis that have a biochemical response to ursodeoxycholic acid

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

EASL Clinical Practice Guidelines: management of cholestatic liver diseases.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel biotransformation and physiological properties of norursodeoxycholic acid in humans.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholestasis in Rats induced by Taurolithocholate

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental changes of bile acid composition and conjugation in L- and D-bifunctional protein single and double knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Differing effects of nor-ursodeoxycholic or ursodeoxycholic acid on hepatic histology and bile acid metabolism in the rabbit

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of side-chain shortening on the physiologic properties of bile acids: hepatic transport and effect on biliary secretion of 23-nor-ursodeoxycholate in rodents.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23911

7 January 2021

based on heuristic

inferred from DOI database lookup

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